PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription

PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription

The specific post-translational modifications of the C-terminal domain (CTD) of the Rpb1 subunit of RNA polymerase II (RNAPII) correlate with different stages of transcription. The phosphorylation of the Ser5 residues of this domain associates with the initiation condensates, which are formed throug...

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Bibliographic Details
Main Authors: Can Balaban, Martin Sztacho, Ludovica Antiga, Ana Miladinović, Masahiko Harata, Pavel Hozák
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomolecules
Subjects:
PIP2
RNA polymerase II
transcription
phase separation
MPRIP
Online Access:https://www.mdpi.com/2218-273X/13/3/426

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