Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases
Higher plants possess the ability to synthesize a great number of compounds with many different functions, known as secondary metabolites. Polyphenols, a class of flavonoids, are secondary metabolites that play a crucial role in plant adaptation to both biotic and abiotic environments, including UV...
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MDPI AG
2023-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/23/7720 |
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| author | Athanasios S. Arampatzis Aspasia Pampori Eleftheria Droutsa Maria Laskari Panagiotis Karakostas Lazaros Tsalikis Panagiotis Barmpalexis Christos Dordas Andreana N. Assimopoulou |
| author_facet | Athanasios S. Arampatzis Aspasia Pampori Eleftheria Droutsa Maria Laskari Panagiotis Karakostas Lazaros Tsalikis Panagiotis Barmpalexis Christos Dordas Andreana N. Assimopoulou |
| author_sort | Athanasios S. Arampatzis |
| collection | DOAJ |
| description | Higher plants possess the ability to synthesize a great number of compounds with many different functions, known as secondary metabolites. Polyphenols, a class of flavonoids, are secondary metabolites that play a crucial role in plant adaptation to both biotic and abiotic environments, including UV radiation, high light intensity, low/high temperatures, and attacks from pathogens, among others. One of the compounds that has received great attention over the last few years is luteolin. The objective of the current paper is to review the extraction and detection methods of luteolin in plants of the Greek flora, as well as their luteolin content. Furthermore, plant species, crop management and environmental factors can affect luteolin content and/or its derivatives. Luteolin exhibits various biological activities, such as cytotoxic, anti-inflammatory, antioxidant and antibacterial ones. As a result, luteolin has been employed as a bioactive molecule in numerous applications within the food industry and the biomedical field. Among the different available options for managing periodontitis, dental care products containing herbal compounds have been in the spotlight owing to the beneficial pharmacological properties of the bioactive ingredients. In this context, luteolin’s anti-inflammatory activity has been harnessed to combat periodontal disease and promote the restoration of damaged bone tissue. |
| first_indexed | 2024-03-09T01:46:08Z |
| format | Article |
| id | doaj.art-8f84d2121bf1402bb3a390d266a5c58b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T01:46:08Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-8f84d2121bf1402bb3a390d266a5c58b2023-12-08T15:22:08ZengMDPI AGMolecules1420-30492023-11-012823772010.3390/molecules28237720Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal DiseasesAthanasios S. Arampatzis0Aspasia Pampori1Eleftheria Droutsa2Maria Laskari3Panagiotis Karakostas4Lazaros Tsalikis5Panagiotis Barmpalexis6Christos Dordas7Andreana N. Assimopoulou8School of Chemical Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Chemical Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Chemical Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Agriculture, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceNatural Products Research Center of Excellence (NatPro-AUTH), Center for Interdisciplinary Research and Innovation, Aristotle University of Thessaloniki, 57001 Thessaloniki, GreeceSchool of Agriculture, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSchool of Chemical Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceHigher plants possess the ability to synthesize a great number of compounds with many different functions, known as secondary metabolites. Polyphenols, a class of flavonoids, are secondary metabolites that play a crucial role in plant adaptation to both biotic and abiotic environments, including UV radiation, high light intensity, low/high temperatures, and attacks from pathogens, among others. One of the compounds that has received great attention over the last few years is luteolin. The objective of the current paper is to review the extraction and detection methods of luteolin in plants of the Greek flora, as well as their luteolin content. Furthermore, plant species, crop management and environmental factors can affect luteolin content and/or its derivatives. Luteolin exhibits various biological activities, such as cytotoxic, anti-inflammatory, antioxidant and antibacterial ones. As a result, luteolin has been employed as a bioactive molecule in numerous applications within the food industry and the biomedical field. Among the different available options for managing periodontitis, dental care products containing herbal compounds have been in the spotlight owing to the beneficial pharmacological properties of the bioactive ingredients. In this context, luteolin’s anti-inflammatory activity has been harnessed to combat periodontal disease and promote the restoration of damaged bone tissue.https://www.mdpi.com/1420-3049/28/23/7720extractionaromaticmedicinal plantssecondary metabolitespharmaceutical use |
| spellingShingle | Athanasios S. Arampatzis Aspasia Pampori Eleftheria Droutsa Maria Laskari Panagiotis Karakostas Lazaros Tsalikis Panagiotis Barmpalexis Christos Dordas Andreana N. Assimopoulou Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases Molecules extraction aromatic medicinal plants secondary metabolites pharmaceutical use |
| title | Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases |
| title_full | Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases |
| title_fullStr | Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases |
| title_full_unstemmed | Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases |
| title_short | Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases |
| title_sort | occurrence of luteolin in the greek flora isolation of luteolin and its action for the treatment of periodontal diseases |
| topic | extraction aromatic medicinal plants secondary metabolites pharmaceutical use |
| url | https://www.mdpi.com/1420-3049/28/23/7720 |
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