Tin-Free Radical Carboazidation
The radical carboazidation of alkenes could be achieved in water using triethylborane as initiator. This efficient process is complete in one hour at room temperature in an open system. These new tin-free azidation and carboazidation conditions are environmentally friendly and enable react...
| Main Authors: | , |
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2004-04-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/3839 |
| _version_ | 1828125212372107264 |
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| author | Philippe Panchaud Philippe Renaud |
| author_facet | Philippe Panchaud Philippe Renaud |
| author_sort | Philippe Panchaud |
| collection | DOAJ |
| description |
The radical carboazidation of alkenes could be achieved in water using triethylborane as initiator. This efficient process is complete in one hour at room temperature in an open system. These new tin-free azidation and carboazidation conditions are environmentally friendly and enable
reactions to be run with an excess of either the alkene or the radical precursor. Furthermore, 3-pyridinesulfonyl azide could be used in order to avoid tedious purifications, especially when the reaction product has a similar chromatographic behavior to benzenesulfonyl azide, our original
azidation reagent.
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| first_indexed | 2024-04-11T15:17:20Z |
| format | Article |
| id | doaj.art-8f863a9c225f4196b50e92df1a7e5653 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-11T15:17:20Z |
| publishDate | 2004-04-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-8f863a9c225f4196b50e92df1a7e56532022-12-22T04:16:27ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242004-04-0158410.2533/000942904777677920Tin-Free Radical CarboazidationPhilippe PanchaudPhilippe Renaud The radical carboazidation of alkenes could be achieved in water using triethylborane as initiator. This efficient process is complete in one hour at room temperature in an open system. These new tin-free azidation and carboazidation conditions are environmentally friendly and enable reactions to be run with an excess of either the alkene or the radical precursor. Furthermore, 3-pyridinesulfonyl azide could be used in order to avoid tedious purifications, especially when the reaction product has a similar chromatographic behavior to benzenesulfonyl azide, our original azidation reagent. https://chimia.ch/chimia/article/view/3839AminationAzidesRadicalsSynthetic methodsTin-free |
| spellingShingle | Philippe Panchaud Philippe Renaud Tin-Free Radical Carboazidation CHIMIA Amination Azides Radicals Synthetic methods Tin-free |
| title | Tin-Free Radical Carboazidation |
| title_full | Tin-Free Radical Carboazidation |
| title_fullStr | Tin-Free Radical Carboazidation |
| title_full_unstemmed | Tin-Free Radical Carboazidation |
| title_short | Tin-Free Radical Carboazidation |
| title_sort | tin free radical carboazidation |
| topic | Amination Azides Radicals Synthetic methods Tin-free |
| url | https://chimia.ch/chimia/article/view/3839 |
| work_keys_str_mv | AT philippepanchaud tinfreeradicalcarboazidation AT philipperenaud tinfreeradicalcarboazidation |