Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics
The worldwide, extraordinary outbreak of coronavirus pandemic (i.e., COVID-19) and other emerging viral expansions have drawn particular interest to the design and development of novel antiviral, and viricidal, agents, with a broad-spectrum of antiviral activity. The current indispensable challenge...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/13/18/4041 |
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| author | Rakesh Pemmada Xiaoxian Zhu Madhusmita Dash Yubin Zhou Seeram Ramakrishna Xinsheng Peng Vinoy Thomas Sanjeev Jain Himansu Sekhar Nanda |
| author_facet | Rakesh Pemmada Xiaoxian Zhu Madhusmita Dash Yubin Zhou Seeram Ramakrishna Xinsheng Peng Vinoy Thomas Sanjeev Jain Himansu Sekhar Nanda |
| author_sort | Rakesh Pemmada |
| collection | DOAJ |
| description | The worldwide, extraordinary outbreak of coronavirus pandemic (i.e., COVID-19) and other emerging viral expansions have drawn particular interest to the design and development of novel antiviral, and viricidal, agents, with a broad-spectrum of antiviral activity. The current indispensable challenge lies in the development of universal virus repudiation systems that are reusable, and capable of inactivating pathogens, thus reducing risk of infection and transmission. In this review, science-based methods, mechanisms, and procedures, which are implemented in obtaining resultant antiviral coated substrates, used in the destruction of the strains of the different viruses, are reviewed. The constituent antiviral members are classified into a few broad groups, such as polymeric materials, metal ions/metal oxides, and functional nanomaterials, based on the type of materials used at the virus contamination sites. The action mode against enveloped viruses was depicted to vindicate the antiviral mechanism. We also disclose hypothesized strategies for development of a universal and reusable virus deactivation system against the emerging COVID-19. In the surge of the current, alarming scenario of SARS-CoV-2 infections, there is a great necessity for developing highly-innovative antiviral agents to work against the viruses. We hypothesize that some of the antiviral coatings discussed here could exert an inhibitive effect on COVID-19, indicated by the results that the coatings succeeded in obtaining against other enveloped viruses. Consequently, the coatings need to be tested and authenticated, to fabricate a wide range of coated antiviral products such as masks, gowns, surgical drapes, textiles, high-touch surfaces, and other personal protective equipment, aimed at extrication from the COVID-19 pandemic. |
| first_indexed | 2024-03-10T16:23:42Z |
| format | Article |
| id | doaj.art-8f8a0cb8eaea48829039e7401d916e2e |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T16:23:42Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-8f8a0cb8eaea48829039e7401d916e2e2023-11-20T13:27:38ZengMDPI AGMaterials1996-19442020-09-011318404110.3390/ma13184041Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like PandemicsRakesh Pemmada0Xiaoxian Zhu1Madhusmita Dash2Yubin Zhou3Seeram Ramakrishna4Xinsheng Peng5Vinoy Thomas6Sanjeev Jain7Himansu Sekhar Nanda8Biomedical Engineering and Technology Laboratory, Discipline of Mechanical Engineering, PDPM-Indian Institute of Information Technology Design and Manufacturing, Jabalpur 482005, MP, IndiaSchool of Pharmacy, Guangdong Medical University, Dongguan 523808, ChinaSchool of Materials and Metallurgical Engineering, Indian Institute of Technology Bhubaneswar, Arugul, Odisha 752050, IndiaSchool of Pharmacy, Guangdong Medical University, Dongguan 523808, ChinaCentre for Nanofibers and Nanotechnology, Department of Mechanical Engineering, National University of Singapore, Engineering Drive 3, Singapore 117587, SingaporeSchool of Pharmacy, Guangdong Medical University, Dongguan 523808, ChinaDepartment of Materials Science and Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USABiomedical Engineering and Technology Laboratory, Discipline of Mechanical Engineering, PDPM-Indian Institute of Information Technology Design and Manufacturing, Jabalpur 482005, MP, IndiaBiomedical Engineering and Technology Laboratory, Discipline of Mechanical Engineering, PDPM-Indian Institute of Information Technology Design and Manufacturing, Jabalpur 482005, MP, IndiaThe worldwide, extraordinary outbreak of coronavirus pandemic (i.e., COVID-19) and other emerging viral expansions have drawn particular interest to the design and development of novel antiviral, and viricidal, agents, with a broad-spectrum of antiviral activity. The current indispensable challenge lies in the development of universal virus repudiation systems that are reusable, and capable of inactivating pathogens, thus reducing risk of infection and transmission. In this review, science-based methods, mechanisms, and procedures, which are implemented in obtaining resultant antiviral coated substrates, used in the destruction of the strains of the different viruses, are reviewed. The constituent antiviral members are classified into a few broad groups, such as polymeric materials, metal ions/metal oxides, and functional nanomaterials, based on the type of materials used at the virus contamination sites. The action mode against enveloped viruses was depicted to vindicate the antiviral mechanism. We also disclose hypothesized strategies for development of a universal and reusable virus deactivation system against the emerging COVID-19. In the surge of the current, alarming scenario of SARS-CoV-2 infections, there is a great necessity for developing highly-innovative antiviral agents to work against the viruses. We hypothesize that some of the antiviral coatings discussed here could exert an inhibitive effect on COVID-19, indicated by the results that the coatings succeeded in obtaining against other enveloped viruses. Consequently, the coatings need to be tested and authenticated, to fabricate a wide range of coated antiviral products such as masks, gowns, surgical drapes, textiles, high-touch surfaces, and other personal protective equipment, aimed at extrication from the COVID-19 pandemic.https://www.mdpi.com/1996-1944/13/18/4041antiviralcoatingspolymeric materialsnanomaterialsmetal ions and oxidesantiviral products |
| spellingShingle | Rakesh Pemmada Xiaoxian Zhu Madhusmita Dash Yubin Zhou Seeram Ramakrishna Xinsheng Peng Vinoy Thomas Sanjeev Jain Himansu Sekhar Nanda Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics Materials antiviral coatings polymeric materials nanomaterials metal ions and oxides antiviral products |
| title | Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics |
| title_full | Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics |
| title_fullStr | Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics |
| title_full_unstemmed | Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics |
| title_short | Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics |
| title_sort | science based strategies of antiviral coatings with viricidal properties for the covid 19 like pandemics |
| topic | antiviral coatings polymeric materials nanomaterials metal ions and oxides antiviral products |
| url | https://www.mdpi.com/1996-1944/13/18/4041 |
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