A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents

Purpose: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. Methods: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care cent...

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Main Authors: Arvind Kumar Morya, Kirandeep Kaur, Bharat Gurnani, Siddharam S Janti, Ankur Kumar Shrivastava, Antarvedi Tejaswini, Aprajita Sinha, Dharavath Venkatesh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=804;epage=809;aulast=Morya
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author Arvind Kumar Morya
Kirandeep Kaur
Bharat Gurnani
Siddharam S Janti
Ankur Kumar Shrivastava
Antarvedi Tejaswini
Aprajita Sinha
Dharavath Venkatesh
author_facet Arvind Kumar Morya
Kirandeep Kaur
Bharat Gurnani
Siddharam S Janti
Ankur Kumar Shrivastava
Antarvedi Tejaswini
Aprajita Sinha
Dharavath Venkatesh
author_sort Arvind Kumar Morya
collection DOAJ
description Purpose: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. Methods: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care center from January 2021 to August 2022. Twenty-three eyes of 21 anisomyopic and isomyopic amblyopia patients operated for posterior chamber phakic IOL (Eyecryl phakic IOL) as a treatment for amblyopia were included in the study. Patient demographics, pre- and postoperative visual acuity, cycloplegic refraction, anterior and posterior segment examination, intraocular pressure, pachymetry, contrast sensitivity, endothelial count, and patient satisfaction scores were evaluated. Patients were followed up at day 1, 6 weeks, 3 months, and 1 year after surgery, and visual outcomes and complications were documented. Results: The mean age of patients was 14.16 ± 3.49 years (range: 10–19 years). The mean intraocular lens power was − 12.20 diopter spherical (DS) in 23 eyes and − 2.25 diopter cylindrical (DC) in four patients. The mean unaided distant visual acuity (UDVA) and best-corrected visual acuity (BCVA) were 1.39 ± 0.25 and 0.40 ± 0.21 preoperatively on the log of minimum angle of resolution (logMAR) chart. Postoperatively, the visual acuity improved by 2.6 lines in 3 months period and maintained till 1 year. Postsurgery, contrast sensitivity in the amblyopic eyes significantly improved, and the average endothelial loss recorded was 5.78% at 1 year, which was statistically insignificant. Patient satisfaction score was statistically significant, with 4.736/5 recorded on the Likert scale. Conclusion: Posterior chamber phakic IOL is a safe, effective, and alternative method for treating amblyopia patients who are noncompliant with glasses, contact lenses, and keratorefractive procedures.
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spelling doaj.art-8f8f05c166984f4c8f6d7a3fbe553d5a2023-05-18T06:11:44ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-0171380480910.4103/IJO.IJO_2567_22A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescentsArvind Kumar MoryaKirandeep KaurBharat GurnaniSiddharam S JantiAnkur Kumar ShrivastavaAntarvedi TejaswiniAprajita SinhaDharavath VenkateshPurpose: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. Methods: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care center from January 2021 to August 2022. Twenty-three eyes of 21 anisomyopic and isomyopic amblyopia patients operated for posterior chamber phakic IOL (Eyecryl phakic IOL) as a treatment for amblyopia were included in the study. Patient demographics, pre- and postoperative visual acuity, cycloplegic refraction, anterior and posterior segment examination, intraocular pressure, pachymetry, contrast sensitivity, endothelial count, and patient satisfaction scores were evaluated. Patients were followed up at day 1, 6 weeks, 3 months, and 1 year after surgery, and visual outcomes and complications were documented. Results: The mean age of patients was 14.16 ± 3.49 years (range: 10–19 years). The mean intraocular lens power was − 12.20 diopter spherical (DS) in 23 eyes and − 2.25 diopter cylindrical (DC) in four patients. The mean unaided distant visual acuity (UDVA) and best-corrected visual acuity (BCVA) were 1.39 ± 0.25 and 0.40 ± 0.21 preoperatively on the log of minimum angle of resolution (logMAR) chart. Postoperatively, the visual acuity improved by 2.6 lines in 3 months period and maintained till 1 year. Postsurgery, contrast sensitivity in the amblyopic eyes significantly improved, and the average endothelial loss recorded was 5.78% at 1 year, which was statistically insignificant. Patient satisfaction score was statistically significant, with 4.736/5 recorded on the Likert scale. Conclusion: Posterior chamber phakic IOL is a safe, effective, and alternative method for treating amblyopia patients who are noncompliant with glasses, contact lenses, and keratorefractive procedures.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=804;epage=809;aulast=Moryaamblyopiaanisometropiaanisomyopicisomyopicphakic iol
spellingShingle Arvind Kumar Morya
Kirandeep Kaur
Bharat Gurnani
Siddharam S Janti
Ankur Kumar Shrivastava
Antarvedi Tejaswini
Aprajita Sinha
Dharavath Venkatesh
A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
Indian Journal of Ophthalmology
amblyopia
anisometropia
anisomyopic
isomyopic
phakic iol
title A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_full A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_fullStr A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_full_unstemmed A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_short A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_sort clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
topic amblyopia
anisometropia
anisomyopic
isomyopic
phakic iol
url http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=804;epage=809;aulast=Morya
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