Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates
In this case, we report an elderly patient with multiple chronic conditions and prolonged intensive care unit (ICU) stays who had recurrent Candida auris (C. auris) in blood despite antifungal therapy. C. auris was misidentified using conventional automated identification system as Candida haemuloni...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-05-01
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| Series: | International Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971218300419 |
| _version_ | 1818031276240666624 |
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| author | Adnan Alatoom Mohammad Sartawi Karen Lawlor Laila AbdelWareth Jens Thomsen Ahmad Nusair Imran Mirza |
| author_facet | Adnan Alatoom Mohammad Sartawi Karen Lawlor Laila AbdelWareth Jens Thomsen Ahmad Nusair Imran Mirza |
| author_sort | Adnan Alatoom |
| collection | DOAJ |
| description | In this case, we report an elderly patient with multiple chronic conditions and prolonged intensive care unit (ICU) stays who had recurrent Candida auris (C. auris) in blood despite antifungal therapy. C. auris was misidentified using conventional automated identification system as Candida haemulonii resulting in delayed diagnosis. The isolate showed increasing minimum inhibitory concentrations (MICs) to different antifungal drugs and persisted in the patient’s blood before the patient deceased. This is the first case of C. auris reported from the United Arab Emirates (UAE); laboratories should be aware of this Candida species and should confirm suspected cases since it is an emerging multi-drug resistant and health-care associated Candida. Keywords: Candida auris, Multidrug resistant, Healthcare- associated |
| first_indexed | 2024-12-10T05:48:54Z |
| format | Article |
| id | doaj.art-8f941b01488745fcb7301c549a9bb17d |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-10T05:48:54Z |
| publishDate | 2018-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-8f941b01488745fcb7301c549a9bb17d2022-12-22T02:00:06ZengElsevierInternational Journal of Infectious Diseases1201-97122018-05-01703637Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab EmiratesAdnan Alatoom0Mohammad Sartawi1Karen Lawlor2Laila AbdelWareth3Jens Thomsen4Ahmad Nusair5Imran Mirza6Pathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab Emirates; Corresponding author at: Pathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Falah Street, Al-Maryah Island, Abu Dhabi, United Arab Emirates.Pathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab EmiratesPathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab EmiratesPathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab EmiratesDivision of Public Health, Environmental Health Section, Abu Dhabi Department of Health (DoH), Abu Dhabi, United Arab EmiratesMedical Subspecialties Institute, Department of Infectious Diseases, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab EmiratesPathology and Laboratory Medicine Institute, Clinical Microbiology Section, Cleveland Clinic Abu Dhabi, Al-Maryah Island, Abu Dhabi, United Arab EmiratesIn this case, we report an elderly patient with multiple chronic conditions and prolonged intensive care unit (ICU) stays who had recurrent Candida auris (C. auris) in blood despite antifungal therapy. C. auris was misidentified using conventional automated identification system as Candida haemulonii resulting in delayed diagnosis. The isolate showed increasing minimum inhibitory concentrations (MICs) to different antifungal drugs and persisted in the patient’s blood before the patient deceased. This is the first case of C. auris reported from the United Arab Emirates (UAE); laboratories should be aware of this Candida species and should confirm suspected cases since it is an emerging multi-drug resistant and health-care associated Candida. Keywords: Candida auris, Multidrug resistant, Healthcare- associatedhttp://www.sciencedirect.com/science/article/pii/S1201971218300419 |
| spellingShingle | Adnan Alatoom Mohammad Sartawi Karen Lawlor Laila AbdelWareth Jens Thomsen Ahmad Nusair Imran Mirza Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates International Journal of Infectious Diseases |
| title | Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates |
| title_full | Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates |
| title_fullStr | Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates |
| title_full_unstemmed | Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates |
| title_short | Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates |
| title_sort | persistent candidemia despite appropriate fungal therapy first case of candida auris from the united arab emirates |
| url | http://www.sciencedirect.com/science/article/pii/S1201971218300419 |
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