Glucagon-Like Peptide-1 Increases Mitochondrial Biogenesis and Function in INS-1 Rat Insulinoma Cells

Glucagon-Like Peptide-1 Increases Mitochondrial Biogenesis and Function in INS-1 Rat Insulinoma Cells

Glucagon-like peptide-1 (GLP-1) is a gut-derived incretin hormone that increases glucose-stimulated insulin secretion in pancreatic β-cells. Since mitochondrial function is crucial to insulin secretion, we hypothesized that GLP-1 may increase mitochondrial biogenesis in pancreatic β-cells. We treate...

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Bibliographic Details
Main Authors: Mi Yeon Kang, Tae Jung Oh, Young Min Cho
Format: Article
Language:English
Published: Korean Endocrine Society 2015-06-01
Series:Endocrinology and Metabolism
Subjects:
Glucagon-like peptide-1
Mitochondria
Diabetes mellitus
Beta cell
Insulin
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-216.pdf

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