Update on Current Technologies for Deep Brain Stimulation in Parkinson’s Disease

Deep brain stimulation (DBS) is becoming increasingly central in the treatment of patients with Parkinson’s disease and other movement disorders. Recent developments in DBS lead and implantable pulse generator design provide increased flexibility for programming, potentially improving the therapeuti...

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Bibliographic Details
Main Authors: Michelle Paff, Aaron Loh, Can Sarica, Andres M. Lozano, Alfonso Fasano
Format: Article
Language:English
Published: Korean Movement Disorder Society 2020-09-01
Series:Journal of Movement Disorders
Subjects:
Online Access:http://www.e-jmd.org/upload/jmd-20052.pdf
Description
Summary:Deep brain stimulation (DBS) is becoming increasingly central in the treatment of patients with Parkinson’s disease and other movement disorders. Recent developments in DBS lead and implantable pulse generator design provide increased flexibility for programming, potentially improving the therapeutic benefit of stimulation. Directional DBS leads may increase the therapeutic window of stimulation by providing a means of avoiding current spread to structures that might give rise to stimulation-related side effects. Similarly, control of current to individual contacts on a DBS lead allows for shaping of the electric field produced between multiple active contacts. The following review aims to describe the recent developments in DBS system technology and the features of each commercially available DBS system. The advantages of each system are reviewed, and general considerations for choosing the most appropriate system are discussed.
ISSN:2005-940X
2093-4939