Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats
<p>Abstract</p> <p>Background</p> <p>The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2010-01-01
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| Series: | Journal of the International Society of Sports Nutrition |
| Online Access: | http://www.jissn.com/content/7/1/6 |
| _version_ | 1811319710907629568 |
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| author | Costa André Marquezi Marcelo Gualano Bruno Roschel Hamilton Lancha Antonio H |
| author_facet | Costa André Marquezi Marcelo Gualano Bruno Roschel Hamilton Lancha Antonio H |
| author_sort | Costa André |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermittent exercise in rats.</p> <p>Methods</p> <p>First, the animals were submitted to a high intensity intermittent maximal swimming exercise protocol to ensure that CR-supplementation was able to delay fatigue (experiment 1). Then, the CR-mediated glycogen sparing effect was examined using a high intensity intermittent sub-maximal exercise test (fixed number of bouts; six bouts of 30-second duration interspersed by two-minute rest interval) (experiment 2). For both experiments, male Wistar rats were given either CR supplementation or placebo (Pl) for 5 days.</p> <p>Results</p> <p>As expected, CR-supplemented animals were able to exercise for a significant higher number of bouts than Pl. Experiment 2 revealed a higher gastrocnemius glycogen content for the CR <it>vs</it>. the Pl group (33.59%). Additionally, CR animals presented lower blood lactate concentrations throughout the intermittent exercise bouts compared to Pl. No difference was found between groups in soleus glycogen content.</p> <p>Conclusion</p> <p>The major finding of this study is that CR supplementation was able to spare muscle glycogen during a high intensity intermittent exercise in rats.</p> |
| first_indexed | 2024-04-13T12:47:26Z |
| format | Article |
| id | doaj.art-8f9aed76620d43c2b95470ba0209224e |
| institution | Directory Open Access Journal |
| issn | 1550-2783 |
| language | English |
| last_indexed | 2024-04-13T12:47:26Z |
| publishDate | 2010-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of the International Society of Sports Nutrition |
| spelling | doaj.art-8f9aed76620d43c2b95470ba0209224e2022-12-22T02:46:20ZengTaylor & Francis GroupJournal of the International Society of Sports Nutrition1550-27832010-01-0171610.1186/1550-2783-7-6Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in ratsCosta AndréMarquezi MarceloGualano BrunoRoschel HamiltonLancha Antonio H<p>Abstract</p> <p>Background</p> <p>The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermittent exercise in rats.</p> <p>Methods</p> <p>First, the animals were submitted to a high intensity intermittent maximal swimming exercise protocol to ensure that CR-supplementation was able to delay fatigue (experiment 1). Then, the CR-mediated glycogen sparing effect was examined using a high intensity intermittent sub-maximal exercise test (fixed number of bouts; six bouts of 30-second duration interspersed by two-minute rest interval) (experiment 2). For both experiments, male Wistar rats were given either CR supplementation or placebo (Pl) for 5 days.</p> <p>Results</p> <p>As expected, CR-supplemented animals were able to exercise for a significant higher number of bouts than Pl. Experiment 2 revealed a higher gastrocnemius glycogen content for the CR <it>vs</it>. the Pl group (33.59%). Additionally, CR animals presented lower blood lactate concentrations throughout the intermittent exercise bouts compared to Pl. No difference was found between groups in soleus glycogen content.</p> <p>Conclusion</p> <p>The major finding of this study is that CR supplementation was able to spare muscle glycogen during a high intensity intermittent exercise in rats.</p>http://www.jissn.com/content/7/1/6 |
| spellingShingle | Costa André Marquezi Marcelo Gualano Bruno Roschel Hamilton Lancha Antonio H Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats Journal of the International Society of Sports Nutrition |
| title | Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| title_full | Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| title_fullStr | Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| title_full_unstemmed | Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| title_short | Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| title_sort | creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats |
| url | http://www.jissn.com/content/7/1/6 |
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