Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation
Previous work demonstrates that nidopallium caudolaterale, which is considered to be an analog of the mammalian prefrontal cortex, participates in goal-directed navigation in pigeons. However, its role remains unclear. To clarify its role, two goal-directed navigation tasks in plus-maze were designe...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2021-12-01
|
| Series: | Journal of Integrative Neuroscience |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/JIN/20/4/10.31083/j.jin2004095 |
| _version_ | 1818013254565232640 |
|---|---|
| author | Xinyu Liu Yang Yang Yanna Ping Kun Zhao Dongyun Wang Hang Xie |
| author_facet | Xinyu Liu Yang Yang Yanna Ping Kun Zhao Dongyun Wang Hang Xie |
| author_sort | Xinyu Liu |
| collection | DOAJ |
| description | Previous work demonstrates that nidopallium caudolaterale, which is considered to be an analog of the mammalian prefrontal cortex, participates in goal-directed navigation in pigeons. However, its role remains unclear. To clarify its role, two goal-directed navigation tasks in plus-maze were designed, in which the goal location of one is random, and the other is fixed, i.e., the random-goal task and the fixed-goal task. The animals were trained to run from the starting location to the goal location in accordance with the cue in the plus-maze. The goal location is variable for the random-goal task but unchanged for the fixed-goal task. The results have demonstrated that the time point of nidopallium caudolaterale neuron response is consistent with decision-making. During the decision-making, the firing rates significantly increased in two tasks, which can also decode the direction of upcoming movement in the random-goal task. However, the location of decision-making is different between the tasks mentioned above. The decision-making window is at the intersection in the random-goal task, which is a departure in the fixed-goal task. In addition, these results also provide evidence that the neural activities obtained from the nidopallium caudolaterale may contain the decision-making information during goal-directed navigation. These results suggest that the avian nidopallium caudolaterale and the mammalian prefrontal cortex may play a similar role in goal-directed spatial decision-making. Additionally, these also may provide some support to understand the neural mechanism of decision-making for different species. |
| first_indexed | 2024-04-14T06:30:53Z |
| format | Article |
| id | doaj.art-8fa07059302e4384a027c1732df27d67 |
| institution | Directory Open Access Journal |
| issn | 1757-448X |
| language | English |
| last_indexed | 2024-04-14T06:30:53Z |
| publishDate | 2021-12-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Journal of Integrative Neuroscience |
| spelling | doaj.art-8fa07059302e4384a027c1732df27d672022-12-22T02:07:38ZengIMR PressJournal of Integrative Neuroscience1757-448X2021-12-0120494595410.31083/j.jin2004095S0219-6352(21)00242-4Avian nidopallium caudolaterale mediates decision-making during goal-directed navigationXinyu Liu0Yang Yang1Yanna Ping2Kun Zhao3Dongyun Wang4Hang Xie5School of Intelligent Manufacturing, Huanghuai University, 463000 Zhumadian, Henan, ChinaDepartment of Neurosurgery, Zhumadian Central Hospital, 463000 Zhumadian, Henan, ChinaSchool of Intelligent Manufacturing, Huanghuai University, 463000 Zhumadian, Henan, ChinaSchool of Electrical Engineering, Zhengzhou University, 450001 Zhengzhou, Henan, ChinaSchool of Intelligent Manufacturing, Huanghuai University, 463000 Zhumadian, Henan, ChinaSchool of Intelligent Manufacturing, Huanghuai University, 463000 Zhumadian, Henan, ChinaPrevious work demonstrates that nidopallium caudolaterale, which is considered to be an analog of the mammalian prefrontal cortex, participates in goal-directed navigation in pigeons. However, its role remains unclear. To clarify its role, two goal-directed navigation tasks in plus-maze were designed, in which the goal location of one is random, and the other is fixed, i.e., the random-goal task and the fixed-goal task. The animals were trained to run from the starting location to the goal location in accordance with the cue in the plus-maze. The goal location is variable for the random-goal task but unchanged for the fixed-goal task. The results have demonstrated that the time point of nidopallium caudolaterale neuron response is consistent with decision-making. During the decision-making, the firing rates significantly increased in two tasks, which can also decode the direction of upcoming movement in the random-goal task. However, the location of decision-making is different between the tasks mentioned above. The decision-making window is at the intersection in the random-goal task, which is a departure in the fixed-goal task. In addition, these results also provide evidence that the neural activities obtained from the nidopallium caudolaterale may contain the decision-making information during goal-directed navigation. These results suggest that the avian nidopallium caudolaterale and the mammalian prefrontal cortex may play a similar role in goal-directed spatial decision-making. Additionally, these also may provide some support to understand the neural mechanism of decision-making for different species.https://www.imrpress.com/journal/JIN/20/4/10.31083/j.jin2004095pigeonsnidopallium caudolateraledecision-makinggoal-directed navigationprefrontal cortex |
| spellingShingle | Xinyu Liu Yang Yang Yanna Ping Kun Zhao Dongyun Wang Hang Xie Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation Journal of Integrative Neuroscience pigeons nidopallium caudolaterale decision-making goal-directed navigation prefrontal cortex |
| title | Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation |
| title_full | Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation |
| title_fullStr | Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation |
| title_full_unstemmed | Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation |
| title_short | Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation |
| title_sort | avian nidopallium caudolaterale mediates decision making during goal directed navigation |
| topic | pigeons nidopallium caudolaterale decision-making goal-directed navigation prefrontal cortex |
| url | https://www.imrpress.com/journal/JIN/20/4/10.31083/j.jin2004095 |
| work_keys_str_mv | AT xinyuliu aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation AT yangyang aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation AT yannaping aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation AT kunzhao aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation AT dongyunwang aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation AT hangxie aviannidopalliumcaudolateralemediatesdecisionmakingduringgoaldirectednavigation |