Differential Expression of Endogenous Retroviruses and Inflammatory Mediators in Female and Male Offspring in a Mouse Model of Maternal Immune Activation

Differential Expression of Endogenous Retroviruses and Inflammatory Mediators in Female and Male Offspring in a Mouse Model of Maternal Immune Activation

Maternal infections during pregnancy and the consequent maternal immune activation (MIA) are the major risk factors for autism spectrum disorder (ASD). Epidemiological evidence is corroborated by the preclinical models in which MIA leads to ASD-like behavioral abnormalities and altered neuroinflamma...

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Bibliographic Details
Main Authors: Chiara Cipriani, Anna Maria Tartaglione, Martina Giudice, Erica D’Avorio, Vita Petrone, Nicola Toschi, Flavia Chiarotti, Martino Tony Miele, Gemma Calamandrei, Enrico Garaci, Claudia Matteucci, Paola Sinibaldi-Vallebona, Laura Ricceri, Emanuela Balestrieri
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
endogenous retroviruses (ERVs)
autism spectrum disorder
social behavior
Poly I:C
cytokines
neuroinflammation
Online Access:https://www.mdpi.com/1422-0067/23/22/13930

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