Thermogenetic neurostimulation with single-cell resolution
Current approaches to thermogenetic manipulation of neuronal activity lack sufficient spatiotemporal resolution. Here the authors show that neurons expressing snake TRPA1 channels are activated at high temporal resolution with IR light and this technique can be used to elicit behaviour in zebrafish...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15362 |
| _version_ | 1830083051561943040 |
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| author | Yulia G. Ermakova Aleksandr A. Lanin Ilya V. Fedotov Matvey Roshchin Ilya V. Kelmanson Dmitry Kulik Yulia A. Bogdanova Arina G. Shokhina Dmitry S. Bilan Dmitry B. Staroverov Pavel M. Balaban Andrei B. Fedotov Dmitry A. Sidorov-Biryukov Evgeny S. Nikitin Aleksei M. Zheltikov Vsevolod V. Belousov |
| author_facet | Yulia G. Ermakova Aleksandr A. Lanin Ilya V. Fedotov Matvey Roshchin Ilya V. Kelmanson Dmitry Kulik Yulia A. Bogdanova Arina G. Shokhina Dmitry S. Bilan Dmitry B. Staroverov Pavel M. Balaban Andrei B. Fedotov Dmitry A. Sidorov-Biryukov Evgeny S. Nikitin Aleksei M. Zheltikov Vsevolod V. Belousov |
| author_sort | Yulia G. Ermakova |
| collection | DOAJ |
| description | Current approaches to thermogenetic manipulation of neuronal activity lack sufficient spatiotemporal resolution. Here the authors show that neurons expressing snake TRPA1 channels are activated at high temporal resolution with IR light and this technique can be used to elicit behaviour in zebrafish larvae. |
| first_indexed | 2024-12-14T16:14:39Z |
| format | Article |
| id | doaj.art-8fa5f9b23ffb42af95a59011913d928a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T16:14:39Z |
| publishDate | 2017-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8fa5f9b23ffb42af95a59011913d928a2022-12-21T22:54:56ZengNature PortfolioNature Communications2041-17232017-05-018111510.1038/ncomms15362Thermogenetic neurostimulation with single-cell resolutionYulia G. Ermakova0Aleksandr A. Lanin1Ilya V. Fedotov2Matvey Roshchin3Ilya V. Kelmanson4Dmitry Kulik5Yulia A. Bogdanova6Arina G. Shokhina7Dmitry S. Bilan8Dmitry B. Staroverov9Pavel M. Balaban10Andrei B. Fedotov11Dmitry A. Sidorov-Biryukov12Evgeny S. Nikitin13Aleksei M. Zheltikov14Vsevolod V. Belousov15Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityInstitute of Higher Nervous Activity and NeurophysiologyShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesInstitute of Higher Nervous Activity and NeurophysiologyPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityInstitute of Higher Nervous Activity and NeurophysiologyPhysics Department, International Laser Center, M.V. Lomonosov Moscow State UniversityShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesCurrent approaches to thermogenetic manipulation of neuronal activity lack sufficient spatiotemporal resolution. Here the authors show that neurons expressing snake TRPA1 channels are activated at high temporal resolution with IR light and this technique can be used to elicit behaviour in zebrafish larvae.https://doi.org/10.1038/ncomms15362 |
| spellingShingle | Yulia G. Ermakova Aleksandr A. Lanin Ilya V. Fedotov Matvey Roshchin Ilya V. Kelmanson Dmitry Kulik Yulia A. Bogdanova Arina G. Shokhina Dmitry S. Bilan Dmitry B. Staroverov Pavel M. Balaban Andrei B. Fedotov Dmitry A. Sidorov-Biryukov Evgeny S. Nikitin Aleksei M. Zheltikov Vsevolod V. Belousov Thermogenetic neurostimulation with single-cell resolution Nature Communications |
| title | Thermogenetic neurostimulation with single-cell resolution |
| title_full | Thermogenetic neurostimulation with single-cell resolution |
| title_fullStr | Thermogenetic neurostimulation with single-cell resolution |
| title_full_unstemmed | Thermogenetic neurostimulation with single-cell resolution |
| title_short | Thermogenetic neurostimulation with single-cell resolution |
| title_sort | thermogenetic neurostimulation with single cell resolution |
| url | https://doi.org/10.1038/ncomms15362 |
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