Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during <italic toggle="yes">Legionella</italic> Infection

ABSTRACT The causative agent of Legionnaires’ disease, Legionella pneumophila, replicates in amoebae and macrophages in a distinct membrane-bound compartment, the Legionella-containing vacuole (LCV). LCV formation is governed by the bacterial Icm/Dot type IV secretion system that translocates ~300 d...

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Bibliographic Details
Main Authors: Stephen Weber, Maria Wagner, Hubert Hilbi
Format: Article
Language:English
Published: American Society for Microbiology 2014-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00839-13