Preparation and Statistical Modeling of Solid Lipid Nanoparticles of Dimethyl Fumarate for Better Management of Multiple Sclerosis

Preparation and Statistical Modeling of Solid Lipid Nanoparticles of Dimethyl Fumarate for Better Management of Multiple Sclerosis

Purpose: The objective of this study was to synthesize and statistically optimize dimethyl fumarate (DMF) loaded solid lipid nanoparticles (SLNs) for better management of multiple sclerosis (MS). Methods: SLNs were formulated by hot emulsion, ultrasonication method and optimized with response surfac...

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Bibliographic Details
Main Authors: Smriti Ojha, Babita Kumar
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Box-behnken design
Dimethyl Fumarate
Multiple Sclerosis
Response Surface Method
Solid lipid nanoparticles
Polydispersity index
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-225.pdf

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