Multifaceted Microcephaly-Related Gene MCPH1

Multifaceted Microcephaly-Related Gene MCPH1

MCPH1, or BRIT1, is often mutated in human primary microcephaly type 1, a neurodevelopmental disorder characterized by a smaller brain size at birth, due to its dysfunction in regulating the proliferation and self-renewal of neuroprogenitor cells. In the last 20 years or so, genetic and cellular stu...

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Bibliographic Details
Main Authors:	Martina Kristofova, Alessandro Ori, Zhao-Qi Wang
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Cells
Subjects:	MCPH neurogenesis gonad development tumorigenesis mouse models
Online Access:	https://www.mdpi.com/2073-4409/11/2/275

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