Genetic differences between Mestizo populations of Bolivia and Peru
Data on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated Amerindian tribes, and that Peruvian and Bolivian...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Institut Français d'Études Andines
2003-03-01
|
| Series: | Bulletin de l'Institut Français d'Études Andines |
| Subjects: | |
| Online Access: | https://journals.openedition.org/bifea/6500 |
| _version_ | 1797308086855139328 |
|---|---|
| author | Jorge Cervantes |
| author_facet | Jorge Cervantes |
| author_sort | Jorge Cervantes |
| collection | DOAJ |
| description | Data on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated Amerindian tribes, and that Peruvian and Bolivian mestizos are closely genetically related. Using Reverse Line Blot Assay, HLA typing for Class I (HLA-A, HLA-B, and HLA-Cw) as well as for Class II (HLA-DRB1 and HLA-DQB1) alleles was performed in 57 Bolivian mestizos. Subjects came mainly from La Paz (the main city in the Bolivian Andes) and three other important cities located in the Bolivian Central Valley (Sucre, Tarija and Tupiza). Comparison of the allele frequencies of Bolivian mestizos with available data from the literature from Peruvian mestizos, revealed that Class I HLA-Cw*01, and B*40 alleles were higher in the Peruvian mestizo group (Chi-sq = 4,87 p |
| first_indexed | 2024-03-08T01:05:37Z |
| format | Article |
| id | doaj.art-8fb6e788ec0d473fa6f802e6bb529530 |
| institution | Directory Open Access Journal |
| issn | 0303-7495 2076-5827 |
| language | Spanish |
| last_indexed | 2024-03-08T01:05:37Z |
| publishDate | 2003-03-01 |
| publisher | Institut Français d'Études Andines |
| record_format | Article |
| series | Bulletin de l'Institut Français d'Études Andines |
| spelling | doaj.art-8fb6e788ec0d473fa6f802e6bb5295302024-02-14T16:32:50ZspaInstitut Français d'Études AndinesBulletin de l'Institut Français d'Études Andines0303-74952076-58272003-03-013221322210.4000/bifea.6500Genetic differences between Mestizo populations of Bolivia and PeruJorge CervantesData on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated Amerindian tribes, and that Peruvian and Bolivian mestizos are closely genetically related. Using Reverse Line Blot Assay, HLA typing for Class I (HLA-A, HLA-B, and HLA-Cw) as well as for Class II (HLA-DRB1 and HLA-DQB1) alleles was performed in 57 Bolivian mestizos. Subjects came mainly from La Paz (the main city in the Bolivian Andes) and three other important cities located in the Bolivian Central Valley (Sucre, Tarija and Tupiza). Comparison of the allele frequencies of Bolivian mestizos with available data from the literature from Peruvian mestizos, revealed that Class I HLA-Cw*01, and B*40 alleles were higher in the Peruvian mestizo group (Chi-sq = 4,87 phttps://journals.openedition.org/bifea/6500MestizoHLAalleleDNA |
| spellingShingle | Jorge Cervantes Genetic differences between Mestizo populations of Bolivia and Peru Bulletin de l'Institut Français d'Études Andines Mestizo HLA allele DNA |
| title | Genetic differences between Mestizo populations of Bolivia and Peru |
| title_full | Genetic differences between Mestizo populations of Bolivia and Peru |
| title_fullStr | Genetic differences between Mestizo populations of Bolivia and Peru |
| title_full_unstemmed | Genetic differences between Mestizo populations of Bolivia and Peru |
| title_short | Genetic differences between Mestizo populations of Bolivia and Peru |
| title_sort | genetic differences between mestizo populations of bolivia and peru |
| topic | Mestizo HLA allele DNA |
| url | https://journals.openedition.org/bifea/6500 |
| work_keys_str_mv | AT jorgecervantes geneticdifferencesbetweenmestizopopulationsofboliviaandperu |