Isolated neutropenia as a rare but serious adverse event secondary to immune checkpoint inhibition

Isolated neutropenia as a rare but serious adverse event secondary to immune checkpoint inhibition

Abstract Background Compared to conventional chemotherapy, Immune checkpoint inhibitors (ICI) are known to have a distinct toxicity profile commonly identified as immune-related adverse events (irAEs). These irAEs that are believed to be related to immune dysregulations triggered by ICI can be serio...

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Bibliographic Details
Main Authors: Abdul Rafeh Naqash, Ebenezer Appah, Li V. Yang, Mahvish Muzaffar, Mona A. Marie, Justin D. Mccallen, Shravanti Macherla, Darla Liles, Paul R. Walker
Format: Article
Language:English
Published: BMJ Publishing Group 2019-07-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Immune checkpoint inhibitors
Neutropenia
Immune-related adverse event
C-reactive protein
IL-6
Immunosuppression
Online Access:http://link.springer.com/article/10.1186/s40425-019-0648-3

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