Acute promyelocytic leukemia with FIP1L1::RARA fusion gene: The clinical utility of transcriptome sequencing and bioinformatic analyses

Acute promyelocytic leukemia with FIP1L1::RARA fusion gene: The clinical utility of transcriptome sequencing and bioinformatic analyses

BackgroundAcute promyelocytic leukemia (APL) is typically characterized by the presence of coagulopathy and the PML::RARA fusion gene. The FIP1L1::RARA has been reported as a novel fusion gene, but studies on its pathogenesis are limited.ObjectivesA FIP1L1::RARA fusion in a child finally diagnosed a...

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Bibliographic Details
Main Authors: Guanghua Liu, Jiangwen Long, Yuyu Chen, Lingqian Li, Xisha Huan, Panpan Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
acute promyelocytic leukemia
FIP1L1::RARA
transcriptome sequencing
bioinformatic analyses
differential expression genes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1049473/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1049473/full

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