Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis
INTRODUCTION In this research we study the effect of Nasal decongestant Xylometazoline 0.1% solution on Serial measurements of Nasal peak flow rates in a cohort of patients who were suffering from Acute Sinusitis. CASE SERIES A population of 90 patients were chosen from our regular Out-pati...
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| Format: | Article |
| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2020-07-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
| Subjects: | |
| Online Access: | https://bjohns.in/journal3/index.php/bjohns/article/view/265 |
| _version_ | 1797284670401937408 |
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| author | Santhosh Kumar Rajamani |
| author_facet | Santhosh Kumar Rajamani |
| author_sort | Santhosh Kumar Rajamani |
| collection | DOAJ |
| description | INTRODUCTION
In this research we study the effect of Nasal decongestant Xylometazoline 0.1% solution on Serial measurements of Nasal peak flow rates in a cohort of patients who were suffering from Acute Sinusitis.
CASE SERIES
A population of 90 patients were chosen from our regular Out-patient clinics who were suffering from Acute Sinusitis based on a Clinical diagnostic criterion. A baseline Nasal peak Flowmetry was done before and this was followed by common Decongestant Xylometazoline 0.1% solution spray application, followed by serial readings of Nasal peak Flowmetry done after 10 minutes, 25 minutes, 60 minutes, 120 minutes,240 minutes and 360 was taken then plotted and analysed.
DISCUSSION
From the A.U.C Curves it can be inferred that Maximum decongestant action of Xylometazoline 0.1% solution is seen 1 hour after application and the raise in decongestant reaches a plateau by 2 hours. Readings remain elevated from baseline well 6 hours post decongestion.
CONCLUSION
Patients who are prescribed Xylometazoline 0.1% solution are advised that maximum relief from congestion would be obtained around 1 to 2 hours after application and hence effect would decrease. Surgeons who use Xylometazoline 0.1% solution for nasal packing must proceed with the Surgery within 1 hour of application of the pack to obtain maximum hemostatic and decongestant benefit of this drug. |
| first_indexed | 2024-03-07T17:51:56Z |
| format | Article |
| id | doaj.art-8fbb8eb2dbea4d4697d41b5933e2f152 |
| institution | Directory Open Access Journal |
| issn | 2395-2407 |
| language | English |
| last_indexed | 2024-03-07T17:51:56Z |
| publishDate | 2020-07-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj.art-8fbb8eb2dbea4d4697d41b5933e2f1522024-03-02T13:52:22ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072020-07-0126210.47210/bjohns.2018.v26i2.265Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute SinusitisSanthosh Kumar Rajamani0BLK Walawalkar Rural Medical college Maharashtra University of Health Sciences (MUHS)INTRODUCTION In this research we study the effect of Nasal decongestant Xylometazoline 0.1% solution on Serial measurements of Nasal peak flow rates in a cohort of patients who were suffering from Acute Sinusitis. CASE SERIES A population of 90 patients were chosen from our regular Out-patient clinics who were suffering from Acute Sinusitis based on a Clinical diagnostic criterion. A baseline Nasal peak Flowmetry was done before and this was followed by common Decongestant Xylometazoline 0.1% solution spray application, followed by serial readings of Nasal peak Flowmetry done after 10 minutes, 25 minutes, 60 minutes, 120 minutes,240 minutes and 360 was taken then plotted and analysed. DISCUSSION From the A.U.C Curves it can be inferred that Maximum decongestant action of Xylometazoline 0.1% solution is seen 1 hour after application and the raise in decongestant reaches a plateau by 2 hours. Readings remain elevated from baseline well 6 hours post decongestion. CONCLUSION Patients who are prescribed Xylometazoline 0.1% solution are advised that maximum relief from congestion would be obtained around 1 to 2 hours after application and hence effect would decrease. Surgeons who use Xylometazoline 0.1% solution for nasal packing must proceed with the Surgery within 1 hour of application of the pack to obtain maximum hemostatic and decongestant benefit of this drug.https://bjohns.in/journal3/index.php/bjohns/article/view/265nasal obstruction measurementnasal patencypeak expiratory flowpeak nasal inspiratory flowRhinosinusitis |
| spellingShingle | Santhosh Kumar Rajamani Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis Bengal Journal of Otolaryngology and Head Neck Surgery nasal obstruction measurement nasal patency peak expiratory flow peak nasal inspiratory flow Rhinosinusitis |
| title | Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis |
| title_full | Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis |
| title_fullStr | Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis |
| title_full_unstemmed | Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis |
| title_short | Effect of Topical Nasal Decongestants on Nasal Peak Flow Rates in Adults Suffering from Acute Sinusitis |
| title_sort | effect of topical nasal decongestants on nasal peak flow rates in adults suffering from acute sinusitis |
| topic | nasal obstruction measurement nasal patency peak expiratory flow peak nasal inspiratory flow Rhinosinusitis |
| url | https://bjohns.in/journal3/index.php/bjohns/article/view/265 |
| work_keys_str_mv | AT santhoshkumarrajamani effectoftopicalnasaldecongestantsonnasalpeakflowratesinadultssufferingfromacutesinusitis |