Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients
Vitiligo is an acquired depigmenting disorder. To date, there is no predictive model for its response rate to narrowband ultraviolet B (NBUVB) phototherapy. The aim of this study was to investigate the different types of response of patients with non-segmental vitiligo undergoing NBUVB 3 times a wee...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2018-01-01
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| Series: | Acta Dermato-Venereologica |
| Subjects: | |
| Online Access: |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2889
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| _version_ | 1818960362741956608 |
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| author | Raúl Cabrera Lia Hojman Francisca Recule Rodrigo Sepulveda Iris Delgado |
| author_facet | Raúl Cabrera Lia Hojman Francisca Recule Rodrigo Sepulveda Iris Delgado |
| author_sort | Raúl Cabrera |
| collection | DOAJ |
| description | Vitiligo is an acquired depigmenting disorder. To date, there is no predictive model for its response rate to narrowband ultraviolet B (NBUVB) phototherapy. The aim of this study was to investigate the different types of response of patients with non-segmental vitiligo undergoing NBUVB 3 times a week. Many patients who were previously considered non-responders were given the opportunity to continue the treatment. Long-term maintenance of treatment and follow-up of a cohort of 579 patients enabled different subtypes of response (very rapid, rapid, average, slow and “non-responders”) to be described for the first time, and a predictive model of response to be constructed based on repigmentation rate in the first 48 sessions of NBUVB. Among those patients who did not respond during the first 48 sessions, a new subgroup of patients was found, termed “very-slow” responders, who achieved a low, but significant, level of repigmentation after 96 sessions of NBUVB. |
| first_indexed | 2024-12-20T11:56:20Z |
| format | Article |
| id | doaj.art-8fbcc71f760c4647bbc0a38a0829ef61 |
| institution | Directory Open Access Journal |
| issn | 0001-5555 1651-2057 |
| language | English |
| last_indexed | 2024-12-20T11:56:20Z |
| publishDate | 2018-01-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Dermato-Venereologica |
| spelling | doaj.art-8fbcc71f760c4647bbc0a38a0829ef612022-12-21T19:41:38ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572018-01-0198441642010.2340/00015555-28895161Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 PatientsRaúl Cabrera0Lia HojmanFrancisca ReculeRodrigo SepulvedaIris Delgado Department of Dermatology, Clinica Alemana de Santiago, Universidad del Desarrollo, Av. Manquehue Norte 1410, Vitacura, Santiago, Chile. rcabrera@alemana.cl. Vitiligo is an acquired depigmenting disorder. To date, there is no predictive model for its response rate to narrowband ultraviolet B (NBUVB) phototherapy. The aim of this study was to investigate the different types of response of patients with non-segmental vitiligo undergoing NBUVB 3 times a week. Many patients who were previously considered non-responders were given the opportunity to continue the treatment. Long-term maintenance of treatment and follow-up of a cohort of 579 patients enabled different subtypes of response (very rapid, rapid, average, slow and “non-responders”) to be described for the first time, and a predictive model of response to be constructed based on repigmentation rate in the first 48 sessions of NBUVB. Among those patients who did not respond during the first 48 sessions, a new subgroup of patients was found, termed “very-slow” responders, who achieved a low, but significant, level of repigmentation after 96 sessions of NBUVB. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2889 vitiligophototherapyultravioletnarrowbandUVBpredictivemodel |
| spellingShingle | Raúl Cabrera Lia Hojman Francisca Recule Rodrigo Sepulveda Iris Delgado Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients Acta Dermato-Venereologica vitiligo phototherapy ultraviolet narrowbandUVB predictivemodel |
| title | Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients |
| title_full | Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients |
| title_fullStr | Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients |
| title_full_unstemmed | Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients |
| title_short | Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients |
| title_sort | predictive model for response rate to narrowband ultraviolet b phototherapy in vitiligo a retrospective cohort study of 579 patients |
| topic | vitiligo phototherapy ultraviolet narrowbandUVB predictivemodel |
| url |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2889
|
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