Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients
Background: Our aim was to associate serum uric acid (UA) with muscle mass, strength and functional capacity in kidney transplant patients (KTPs). Methods: A cross-sectional study was performed on 113 KTPs. The fat-free mass and total and appendicular muscle mass were estimated by performing a bioel...
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| Format: | Article |
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MDPI AG
2020-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/8/2390 |
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| author | João Pedro Floriano Paula C. Nahas Flávia M. S. de Branco Aline S. dos Reis Luana T. Rossato Heitor O. Santos Larissa S. Limirio Sebastião R. Ferreira-Filho Erick P. de Oliveira |
| author_facet | João Pedro Floriano Paula C. Nahas Flávia M. S. de Branco Aline S. dos Reis Luana T. Rossato Heitor O. Santos Larissa S. Limirio Sebastião R. Ferreira-Filho Erick P. de Oliveira |
| author_sort | João Pedro Floriano |
| collection | DOAJ |
| description | Background: Our aim was to associate serum uric acid (UA) with muscle mass, strength and functional capacity in kidney transplant patients (KTPs). Methods: A cross-sectional study was performed on 113 KTPs. The fat-free mass and total and appendicular muscle mass were estimated by performing a bioelectrical impedance analysis. The strength was evaluated using the handgrip strength test (HGS) and the five times sit to stand test (5STS). The functional capacity was evaluated using the 4 m walk test and the short physical performance battery (SPPB). Results: Linear regression showed that the UA levels were positively associated with the muscle mass, fat-free mass, appendicular muscle mass, muscle mass index and appendicular muscle mass index. The 5STS results (seconds) were inversely associated with the UA levels, showing that individuals with higher UA were more likely to have more strength. However, UA was not associated with the HGS, 4 m walk test and SPPB results. Conclusion: UA levels were positively associated with muscle mass and strength, but not with functional capacity, in KTPs. |
| first_indexed | 2024-03-10T17:42:58Z |
| format | Article |
| id | doaj.art-8fbd209cc3bc44ada787118552dbb5cf |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T17:42:58Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-8fbd209cc3bc44ada787118552dbb5cf2023-11-20T09:39:07ZengMDPI AGNutrients2072-66432020-08-01128239010.3390/nu12082390Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant PatientsJoão Pedro Floriano0Paula C. Nahas1Flávia M. S. de Branco2Aline S. dos Reis3Luana T. Rossato4Heitor O. Santos5Larissa S. Limirio6Sebastião R. Ferreira-Filho7Erick P. de Oliveira8Laboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilSchool of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, BrazilBackground: Our aim was to associate serum uric acid (UA) with muscle mass, strength and functional capacity in kidney transplant patients (KTPs). Methods: A cross-sectional study was performed on 113 KTPs. The fat-free mass and total and appendicular muscle mass were estimated by performing a bioelectrical impedance analysis. The strength was evaluated using the handgrip strength test (HGS) and the five times sit to stand test (5STS). The functional capacity was evaluated using the 4 m walk test and the short physical performance battery (SPPB). Results: Linear regression showed that the UA levels were positively associated with the muscle mass, fat-free mass, appendicular muscle mass, muscle mass index and appendicular muscle mass index. The 5STS results (seconds) were inversely associated with the UA levels, showing that individuals with higher UA were more likely to have more strength. However, UA was not associated with the HGS, 4 m walk test and SPPB results. Conclusion: UA levels were positively associated with muscle mass and strength, but not with functional capacity, in KTPs.https://www.mdpi.com/2072-6643/12/8/2390uric acidsarcopeniamuscle functionrenal patients |
| spellingShingle | João Pedro Floriano Paula C. Nahas Flávia M. S. de Branco Aline S. dos Reis Luana T. Rossato Heitor O. Santos Larissa S. Limirio Sebastião R. Ferreira-Filho Erick P. de Oliveira Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients Nutrients uric acid sarcopenia muscle function renal patients |
| title | Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients |
| title_full | Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients |
| title_fullStr | Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients |
| title_full_unstemmed | Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients |
| title_short | Serum Uric Acid Is Positively Associated with Muscle Mass and Strength, but Not with Functional Capacity, in Kidney Transplant Patients |
| title_sort | serum uric acid is positively associated with muscle mass and strength but not with functional capacity in kidney transplant patients |
| topic | uric acid sarcopenia muscle function renal patients |
| url | https://www.mdpi.com/2072-6643/12/8/2390 |
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