Radiopharmaceuticals for sentinel node detection
Imaging of sentinel nodes is a valuable technique in the management of some types of cancer. Several different radiopharmaceuticals have been successfully employed in the technique, but there have been few systematic studies to examine the relationship between physicochemical properties of the radio...
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2002-09-01
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| Series: | Brazilian Archives of Biology and Technology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500011 |
| _version_ | 1818269599423004672 |
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| author | Malcolm Frier |
| author_facet | Malcolm Frier |
| author_sort | Malcolm Frier |
| collection | DOAJ |
| description | Imaging of sentinel nodes is a valuable technique in the management of some types of cancer. Several different radiopharmaceuticals have been successfully employed in the technique, but there have been few systematic studies to examine the relationship between physicochemical properties of the radiopharmaceuticals used and in-vivo performance. The present study describes the preparation and characterisation of radiocolloids of similar chemical composition but differing in particle size distribution in an attempt to identify the role of variations in the single parameter of size.<br>A imagem de nódulos sentinelas é uma técnica valiosa no acompanhamento de alguns tipos de câncer. Com esta finalidade diferentes radiofármacos têm sido empregados com sucesso, porém existem poucos estudos sistemáticos examinando a relação entre as propriedades físico-químicas dos radiofármacos utilizados e sua performance in vivo. O presente estudo descreve a preparação e caracterização de radiocolóides com composição química similar diferindo sua distribuição no tamanho das partículas; na tentativa de identificar a importância de variações de tamanho como um único parâmetro. |
| first_indexed | 2024-12-12T20:56:57Z |
| format | Article |
| id | doaj.art-8fbd40259366492abf03924085521868 |
| institution | Directory Open Access Journal |
| issn | 1516-8913 1678-4324 |
| language | English |
| last_indexed | 2024-12-12T20:56:57Z |
| publishDate | 2002-09-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-8fbd40259366492abf039240855218682022-12-22T00:12:16ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43242002-09-0145spe838610.1590/S1516-89132002000500011Radiopharmaceuticals for sentinel node detectionMalcolm FrierImaging of sentinel nodes is a valuable technique in the management of some types of cancer. Several different radiopharmaceuticals have been successfully employed in the technique, but there have been few systematic studies to examine the relationship between physicochemical properties of the radiopharmaceuticals used and in-vivo performance. The present study describes the preparation and characterisation of radiocolloids of similar chemical composition but differing in particle size distribution in an attempt to identify the role of variations in the single parameter of size.<br>A imagem de nódulos sentinelas é uma técnica valiosa no acompanhamento de alguns tipos de câncer. Com esta finalidade diferentes radiofármacos têm sido empregados com sucesso, porém existem poucos estudos sistemáticos examinando a relação entre as propriedades físico-químicas dos radiofármacos utilizados e sua performance in vivo. O presente estudo descreve a preparação e caracterização de radiocolóides com composição química similar diferindo sua distribuição no tamanho das partículas; na tentativa de identificar a importância de variações de tamanho como um único parâmetro.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500011Sentinel noderadiocolloidparticle size |
| spellingShingle | Malcolm Frier Radiopharmaceuticals for sentinel node detection Brazilian Archives of Biology and Technology Sentinel node radiocolloid particle size |
| title | Radiopharmaceuticals for sentinel node detection |
| title_full | Radiopharmaceuticals for sentinel node detection |
| title_fullStr | Radiopharmaceuticals for sentinel node detection |
| title_full_unstemmed | Radiopharmaceuticals for sentinel node detection |
| title_short | Radiopharmaceuticals for sentinel node detection |
| title_sort | radiopharmaceuticals for sentinel node detection |
| topic | Sentinel node radiocolloid particle size |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500011 |
| work_keys_str_mv | AT malcolmfrier radiopharmaceuticalsforsentinelnodedetection |