Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy
Changes in the cornea can influence outcomes in patients with primary open-angle glaucoma (POAG). We aimed to evaluate the relevance of changes in corneal biomechanics and intraocular pressure (IOP) in patients undergoing non-penetrating deep sclerectomy (NPDS) with the Esnoper V2000 implant<sup&...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/5/1216 |
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| author | María Dolores Díaz-Barreda Ignacio Sánchez-Marín Ana Boned-Murillo Itziar Pérez-Navarro Juana Martínez Elena Pardina-Claver Diana Pérez Francisco Javier Ascaso Juan Ibáñez |
| author_facet | María Dolores Díaz-Barreda Ignacio Sánchez-Marín Ana Boned-Murillo Itziar Pérez-Navarro Juana Martínez Elena Pardina-Claver Diana Pérez Francisco Javier Ascaso Juan Ibáñez |
| author_sort | María Dolores Díaz-Barreda |
| collection | DOAJ |
| description | Changes in the cornea can influence outcomes in patients with primary open-angle glaucoma (POAG). We aimed to evaluate the relevance of changes in corneal biomechanics and intraocular pressure (IOP) in patients undergoing non-penetrating deep sclerectomy (NPDS) with the Esnoper V2000 implant<sup>®</sup> (AJL Ophthalmic S.A., Gasteiz, Spain). We included 42 eyes of 42 patients with POAG scheduled for NPDS with the Esnoper V2000 implant. Biomechanical properties were measured by Ocular Response Analyzer<sup>®</sup> G3 (ORA; Reichert Inc., Depew, NY, USA). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) were measured the day before surgery and on day 1, 7, and 30 and 2 and 3 months after surgery. CH initially increased, fell below the presurgical value at 30 days after the surgery, and increased again at 2 and 3 months. CRF, IOPcc, and IOPg decreased on the first day after surgery, then followed a trend of increasing but stayed below pre-surgery levels. All values reached statistical significance. While observed changes in corneal biomechanics after NPDS and Esnoper V2000 implant were significant, more studies are needed if we are to understand their influence on corneal biomechanics and their clinical relevance in POAG. |
| first_indexed | 2024-03-09T20:35:07Z |
| format | Article |
| id | doaj.art-8fbe2f137ac34992a9921fbd981171d1 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T20:35:07Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-8fbe2f137ac34992a9921fbd981171d12023-11-23T23:12:34ZengMDPI AGJournal of Clinical Medicine2077-03832022-02-01115121610.3390/jcm11051216Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep SclerectomyMaría Dolores Díaz-Barreda0Ignacio Sánchez-Marín1Ana Boned-Murillo2Itziar Pérez-Navarro3Juana Martínez4Elena Pardina-Claver5Diana Pérez6Francisco Javier Ascaso7Juan Ibáñez8Department of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainChanges in the cornea can influence outcomes in patients with primary open-angle glaucoma (POAG). We aimed to evaluate the relevance of changes in corneal biomechanics and intraocular pressure (IOP) in patients undergoing non-penetrating deep sclerectomy (NPDS) with the Esnoper V2000 implant<sup>®</sup> (AJL Ophthalmic S.A., Gasteiz, Spain). We included 42 eyes of 42 patients with POAG scheduled for NPDS with the Esnoper V2000 implant. Biomechanical properties were measured by Ocular Response Analyzer<sup>®</sup> G3 (ORA; Reichert Inc., Depew, NY, USA). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) were measured the day before surgery and on day 1, 7, and 30 and 2 and 3 months after surgery. CH initially increased, fell below the presurgical value at 30 days after the surgery, and increased again at 2 and 3 months. CRF, IOPcc, and IOPg decreased on the first day after surgery, then followed a trend of increasing but stayed below pre-surgery levels. All values reached statistical significance. While observed changes in corneal biomechanics after NPDS and Esnoper V2000 implant were significant, more studies are needed if we are to understand their influence on corneal biomechanics and their clinical relevance in POAG.https://www.mdpi.com/2077-0383/11/5/1216corneal biomechanicsocular response analyzerORAcorneal hysteresisglaucomatonometry |
| spellingShingle | María Dolores Díaz-Barreda Ignacio Sánchez-Marín Ana Boned-Murillo Itziar Pérez-Navarro Juana Martínez Elena Pardina-Claver Diana Pérez Francisco Javier Ascaso Juan Ibáñez Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy Journal of Clinical Medicine corneal biomechanics ocular response analyzer ORA corneal hysteresis glaucoma tonometry |
| title | Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy |
| title_full | Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy |
| title_fullStr | Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy |
| title_full_unstemmed | Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy |
| title_short | Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy |
| title_sort | modification of corneal biomechanics and intraocular pressure following non penetrating deep sclerectomy |
| topic | corneal biomechanics ocular response analyzer ORA corneal hysteresis glaucoma tonometry |
| url | https://www.mdpi.com/2077-0383/11/5/1216 |
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