Primary dengue haemorrhagic fever in patients from northeast of Brazil is associated with high levels of interferon-β during acute phase

Primary dengue haemorrhagic fever in patients from northeast of Brazil is associated with high levels of interferon-β during acute phase

Dengue is an acute febrile disease caused by the mosquito-borne dengue virus (DENV) that according to clinical manifestations can be classified as asymptomatic, mild or severe dengue. Severe dengue cases have been associated with an unbalanced immune response characterised by an over secretion of in...

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Bibliographic Details
Main Authors: Renato Antônio dos Santos Oliveira, Mayara Marques Carneiro da Silva, Carlos Eduardo Calzavara-Silva, Ana Maria Silva, Marli Tenório Cordeiro, Patrícia Muniz Mendes Freire de Moura, Paulo Neves Baptista Filho, Ernesto Torres de Azevedo Marques Júnior, Laura Helena Vega Gonzales Gil
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2016-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
dengue fever
dengue haemorrhagic fever
type I interferon
innate immunity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600378&lng=en&tlng=en

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