Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool.

Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool.

Mesodiencephalic dopaminergic (mdDA) neurons are located in the ventral midbrain. These neurons form the substantia nigra (SNc) and the ventral tegmental area (VTA). Two transcription factors that play important roles in the process of terminal differentiation and subset-specification of mdDA neuron...

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Bibliographic Details
Main Authors: Willemieke M Kouwenhoven, Lars von Oerthel, Marten P Smidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5553812?pdf=render

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