Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature

Isotretinoin is widely used in the treatment of acne vulgaris and other dermatological diseases. Numerous side effects have been reported in the literature. A myocardial bridge occurs when segments of the coronary artery create an intramyocardial tunnel. Atherosclerotic plaque formation frequently o...

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Main Authors: Murat Akçay, Serkan Yüksel
Format: Article
Language:English
Published: KARE Publishing 2019-06-01
Series:Türk Kardiyoloji Derneği Arşivi
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-67055
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author Murat Akçay
Serkan Yüksel
author_facet Murat Akçay
Serkan Yüksel
author_sort Murat Akçay
collection DOAJ
description Isotretinoin is widely used in the treatment of acne vulgaris and other dermatological diseases. Numerous side effects have been reported in the literature. A myocardial bridge occurs when segments of the coronary artery create an intramyocardial tunnel. Atherosclerotic plaque formation frequently occurs in the segment proximal to a myocardial bridge. Coronary thrombus formation, which is often the cause of myocardial infarction in young patients, can be triggered by many factors. Kounis syndrome is described as acute coronary syndromes associated with allergic or hypersensitivity reactions. This article is a description of the case of a patient predisposed to the development of a thrombus by a myocardial bridge who was successfully treated for coronary thrombosis and which may represent a case of Kounis syndrome associated with isotretinoin use presented in the context of the relevant literature.
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spelling doaj.art-8fc4a76f66aa4a0782c8bddcf9fb33d72023-02-15T16:08:49ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692019-06-0147432432810.5543/tkda.2018.67055TKDA-67055Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literatureMurat Akçay0Serkan Yüksel1Ondokuz Mayıs University, Faculty Of Medicine, Department Of Cardiology, Samsun, TurkeyOndokuz Mayıs University, Faculty Of Medicine, Department Of Cardiology, Samsun, TurkeyIsotretinoin is widely used in the treatment of acne vulgaris and other dermatological diseases. Numerous side effects have been reported in the literature. A myocardial bridge occurs when segments of the coronary artery create an intramyocardial tunnel. Atherosclerotic plaque formation frequently occurs in the segment proximal to a myocardial bridge. Coronary thrombus formation, which is often the cause of myocardial infarction in young patients, can be triggered by many factors. Kounis syndrome is described as acute coronary syndromes associated with allergic or hypersensitivity reactions. This article is a description of the case of a patient predisposed to the development of a thrombus by a myocardial bridge who was successfully treated for coronary thrombosis and which may represent a case of Kounis syndrome associated with isotretinoin use presented in the context of the relevant literature.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-67055isotretinoinmyocardial bridgecoronary thrombusmyocardial infarctionkounis syndrome
spellingShingle Murat Akçay
Serkan Yüksel
Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
Türk Kardiyoloji Derneği Arşivi
isotretinoin
myocardial bridge
coronary thrombus
myocardial infarction
kounis syndrome
title Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
title_full Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
title_fullStr Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
title_full_unstemmed Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
title_short Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature
title_sort isotretinoin associated possible kounis syndrome a case report and a review of other cardiovascular side effects reported in the literature
topic isotretinoin
myocardial bridge
coronary thrombus
myocardial infarction
kounis syndrome
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-67055
work_keys_str_mv AT muratakcay isotretinoinassociatedpossiblekounissyndromeacasereportandareviewofothercardiovascularsideeffectsreportedintheliterature
AT serkanyuksel isotretinoinassociatedpossiblekounissyndromeacasereportandareviewofothercardiovascularsideeffectsreportedintheliterature