Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial
Abstract Background Adherence to prescribed treatment in chronic diseases, as occurs in multiple sclerosis (MS), is a critical factor for a successful therapeutic response. This study aimed to investigate the effect of educational program based on Theory of Planned Behavior (TPB) on treatment adhere...
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-15910-6 |
| _version_ | 1797811281080614912 |
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| author | Sara Hamtaeigashti Mohsen Shamsi Mohammad Ali Sahraian Raheleh Soltani Amir Almasi-Hashiani |
| author_facet | Sara Hamtaeigashti Mohsen Shamsi Mohammad Ali Sahraian Raheleh Soltani Amir Almasi-Hashiani |
| author_sort | Sara Hamtaeigashti |
| collection | DOAJ |
| description | Abstract Background Adherence to prescribed treatment in chronic diseases, as occurs in multiple sclerosis (MS), is a critical factor for a successful therapeutic response. This study aimed to investigate the effect of educational program based on Theory of Planned Behavior (TPB) on treatment adherence in patients with multiple sclerosis (MS) receiving injectable immunomodulatory drugs. Methods The present study is an educational randomized controlled trial research that was conducted on 100 patients with MS who had gone to MS clinic in Tehran city (Iran). The samples were randomly assigned to the intervention (N = 50) and control groups (N = 50). Data collection instrument was a researcher-made questionnaire based on TPB. Then, educational program was performed for the intervention group through four educational sessions. After three months, data collection was repeated for the two groups and data were analyzed. Results The knowledge and performance of the intervention group on treatment adherence drugs increased from 56.25 ± 20.3 to 78.31 ± 15.57 and 56.22 ± 5.76 to 71.62 ± 12.01 after the education respectively (p < 0.001). The mean of construct of TPB in the intervention group also increased after the intervention (p < 0.05). Conclusion Applying the TPB model proved is very effective in developing an educational program for patients with MS, to enhance treatment adherence drugs. Besides such programs, follow-up education for controlling and monitoring are highly recommended. Trial registration This trial has been registered at Iranian Registry of Clinical Trials, IRCT20210808052109N1. Prospectively registered at 12-Aug-2021, (12/8/2021) available at: URL: https://en.irct.ir/trial/57994 |
| first_indexed | 2024-03-13T07:20:16Z |
| format | Article |
| id | doaj.art-8fc6cb73e8a9400794d6995d91ec6b52 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-13T07:20:16Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-8fc6cb73e8a9400794d6995d91ec6b522023-06-04T11:40:34ZengBMCBMC Public Health1471-24582023-05-0123111310.1186/s12889-023-15910-6Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trialSara Hamtaeigashti0Mohsen Shamsi1Mohammad Ali Sahraian2Raheleh Soltani3Amir Almasi-Hashiani4Department of Health Education, Faculty of Health, Research Committee, Arak University of Medical SciencesDepartment of Health Education and Health Promotion, Faculty of Health, Arak University of Medical SciencesMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University Of Medical SciencesDepartment of Health Education and Health Promotion, Faculty of Health, Arak University of Medical SciencesDepartment of Epidemiology, Faculty of Health, Arak University of Medical SciencesAbstract Background Adherence to prescribed treatment in chronic diseases, as occurs in multiple sclerosis (MS), is a critical factor for a successful therapeutic response. This study aimed to investigate the effect of educational program based on Theory of Planned Behavior (TPB) on treatment adherence in patients with multiple sclerosis (MS) receiving injectable immunomodulatory drugs. Methods The present study is an educational randomized controlled trial research that was conducted on 100 patients with MS who had gone to MS clinic in Tehran city (Iran). The samples were randomly assigned to the intervention (N = 50) and control groups (N = 50). Data collection instrument was a researcher-made questionnaire based on TPB. Then, educational program was performed for the intervention group through four educational sessions. After three months, data collection was repeated for the two groups and data were analyzed. Results The knowledge and performance of the intervention group on treatment adherence drugs increased from 56.25 ± 20.3 to 78.31 ± 15.57 and 56.22 ± 5.76 to 71.62 ± 12.01 after the education respectively (p < 0.001). The mean of construct of TPB in the intervention group also increased after the intervention (p < 0.05). Conclusion Applying the TPB model proved is very effective in developing an educational program for patients with MS, to enhance treatment adherence drugs. Besides such programs, follow-up education for controlling and monitoring are highly recommended. Trial registration This trial has been registered at Iranian Registry of Clinical Trials, IRCT20210808052109N1. Prospectively registered at 12-Aug-2021, (12/8/2021) available at: URL: https://en.irct.ir/trial/57994https://doi.org/10.1186/s12889-023-15910-6Multiple sclerosisTreatment adherence drugsEducational interventionTheory of planned behaviorRandomized controlled trial |
| spellingShingle | Sara Hamtaeigashti Mohsen Shamsi Mohammad Ali Sahraian Raheleh Soltani Amir Almasi-Hashiani Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial BMC Public Health Multiple sclerosis Treatment adherence drugs Educational intervention Theory of planned behavior Randomized controlled trial |
| title | Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial |
| title_full | Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial |
| title_fullStr | Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial |
| title_full_unstemmed | Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial |
| title_short | Effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease-modifying drugs: randomized controlled trial |
| title_sort | effect of an educational intervention based on the theory of planned behavior on improving medication adherence in patients with multiple sclerosis treated with injectable disease modifying drugs randomized controlled trial |
| topic | Multiple sclerosis Treatment adherence drugs Educational intervention Theory of planned behavior Randomized controlled trial |
| url | https://doi.org/10.1186/s12889-023-15910-6 |
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