Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-08-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/16/8/6985/ |
_version_ | 1818484507229028352 |
---|---|
author | Haihong Huang Dali Yin Xiaojian Wang Chun Li Hao Zhang Gang Zhang |
author_facet | Haihong Huang Dali Yin Xiaojian Wang Chun Li Hao Zhang Gang Zhang |
author_sort | Haihong Huang |
collection | DOAJ |
description | New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination. |
first_indexed | 2024-12-10T15:56:29Z |
format | Article |
id | doaj.art-8fc9f75510494ff0ad59b8c291f9811b |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-12-10T15:56:29Z |
publishDate | 2011-08-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-8fc9f75510494ff0ad59b8c291f9811b2022-12-22T01:42:38ZengMDPI AGMolecules1420-30492011-08-011686985699110.3390/molecules16086985Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N PositionHaihong HuangDali YinXiaojian WangChun LiHao ZhangGang ZhangNew riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.http://www.mdpi.com/1420-3049/16/8/6985/riminophenazineN-arylationpalladium catalyst |
spellingShingle | Haihong Huang Dali Yin Xiaojian Wang Chun Li Hao Zhang Gang Zhang Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position Molecules riminophenazine N-arylation palladium catalyst |
title | Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position |
title_full | Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position |
title_fullStr | Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position |
title_full_unstemmed | Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position |
title_short | Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position |
title_sort | synthesis of new riminophenazines with pyrimidine and pyrazine substitution at the 2 n position |
topic | riminophenazine N-arylation palladium catalyst |
url | http://www.mdpi.com/1420-3049/16/8/6985/ |
work_keys_str_mv | AT haihonghuang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition AT daliyin synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition AT xiaojianwang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition AT chunli synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition AT haozhang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition AT gangzhang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition |