HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)

HTLV-I associated myelopathy/tropical spastic paraparesis (TSP/HAM) have been increasingly described in practically all regions of Brazil. Five confirmed and documented cases of patients with TSP/HAM in Rio Grande do Sul are reported; in all of them spastic paraparesis, neurogenic bladder and superf...

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Main Authors: Márcio Menna-Barreto, Alexandre Doval, Giorgio Rabolin, Otomar Bianchini
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 1995-12-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500010
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author Márcio Menna-Barreto
Alexandre Doval
Giorgio Rabolin
Otomar Bianchini
author_facet Márcio Menna-Barreto
Alexandre Doval
Giorgio Rabolin
Otomar Bianchini
author_sort Márcio Menna-Barreto
collection DOAJ
description HTLV-I associated myelopathy/tropical spastic paraparesis (TSP/HAM) have been increasingly described in practically all regions of Brazil. Five confirmed and documented cases of patients with TSP/HAM in Rio Grande do Sul are reported; in all of them spastic paraparesis, neurogenic bladder and superficial and/or profound sensitive disorders were observed in variable degrees. One patient presented a relapsing-remitting course with a cerebellar ataxia (multiple sclerosis-like pattern). Everyone was submitted to clinical, serological, urodynamic, neurophysiologic and neuroradiologic investigation. The aim of this study was to present the southern region of Brazil as an area with significant endemicity for HTLV-I/II infection (prevalence of 0.42% between blood donors), and also to show the existence of patients with neurologic disease associated with this retrovirus.<br>Mielopatia associada ao HTLV-I/paraparesia espástica tropical (TSP/HAM) tem sido descrita de forma crescente em praticamente todas as regiões do Brasil. Relatam-se cinco casos confirmados e documentados de pacientes com TSP/HAM no Rio Grande do Sul, observando-se em todos paraparesia espástica, bexiga neurogênica e distúrbios sensitivos superficiais e/ou profundos de graus variáveis. Em um caso denotou-se padrão em surto e remissão, caracterizado por ataxia cerebelar (sugestivo de esclerose múltipla). Os cinco pacientes foram submetidos a investigação clínica, laboratorial, urodinâmica, neurofisiológicae de neuroimagem. O objetivo do presente trabalho foi apresentar a região sul do Brasil como uma área de significativa endemicidade de infecção por HTLV-I/II (0,42% de prevalência entre doadores de sangue), bem como evidenciar a existência de pacientes com doença neurológica associada a este retrovirus.
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spelling doaj.art-8fca49e956224b36aa0267d66111d9ed2022-12-22T01:58:30ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria0004-282X1678-42271995-12-0153477177610.1590/S0004-282X1995000500010HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)Márcio Menna-BarretoAlexandre DovalGiorgio RabolinOtomar BianchiniHTLV-I associated myelopathy/tropical spastic paraparesis (TSP/HAM) have been increasingly described in practically all regions of Brazil. Five confirmed and documented cases of patients with TSP/HAM in Rio Grande do Sul are reported; in all of them spastic paraparesis, neurogenic bladder and superficial and/or profound sensitive disorders were observed in variable degrees. One patient presented a relapsing-remitting course with a cerebellar ataxia (multiple sclerosis-like pattern). Everyone was submitted to clinical, serological, urodynamic, neurophysiologic and neuroradiologic investigation. The aim of this study was to present the southern region of Brazil as an area with significant endemicity for HTLV-I/II infection (prevalence of 0.42% between blood donors), and also to show the existence of patients with neurologic disease associated with this retrovirus.<br>Mielopatia associada ao HTLV-I/paraparesia espástica tropical (TSP/HAM) tem sido descrita de forma crescente em praticamente todas as regiões do Brasil. Relatam-se cinco casos confirmados e documentados de pacientes com TSP/HAM no Rio Grande do Sul, observando-se em todos paraparesia espástica, bexiga neurogênica e distúrbios sensitivos superficiais e/ou profundos de graus variáveis. Em um caso denotou-se padrão em surto e remissão, caracterizado por ataxia cerebelar (sugestivo de esclerose múltipla). Os cinco pacientes foram submetidos a investigação clínica, laboratorial, urodinâmica, neurofisiológicae de neuroimagem. O objetivo do presente trabalho foi apresentar a região sul do Brasil como uma área de significativa endemicidade de infecção por HTLV-I/II (0,42% de prevalência entre doadores de sangue), bem como evidenciar a existência de pacientes com doença neurológica associada a este retrovirus.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500010HTLV-Imielopatiaparaparesia espástica tropicalbexiga neurogênicaPET/ MAHesclerose múltiplaBrasilHTLV-Imyelopathytropical spastic paraparesisneurogenic bladderTSP/HAMmultiple sclerosisBrazil
spellingShingle Márcio Menna-Barreto
Alexandre Doval
Giorgio Rabolin
Otomar Bianchini
HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
Arquivos de Neuro-Psiquiatria
HTLV-I
mielopatia
paraparesia espástica tropical
bexiga neurogênica
PET/ MAH
esclerose múltipla
Brasil
HTLV-I
myelopathy
tropical spastic paraparesis
neurogenic bladder
TSP/HAM
multiple sclerosis
Brazil
title HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
title_full HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
title_fullStr HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
title_full_unstemmed HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
title_short HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)
title_sort htlv i associated myelopathy in porto alegre southern brazil mielopatia associada ao htlv i em porto alegre sul do brasil
topic HTLV-I
mielopatia
paraparesia espástica tropical
bexiga neurogênica
PET/ MAH
esclerose múltipla
Brasil
HTLV-I
myelopathy
tropical spastic paraparesis
neurogenic bladder
TSP/HAM
multiple sclerosis
Brazil
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500010
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