Critical evaluation of the efficacy and tolerability of azilsartan

Alberto R De Caterina1,2, Andrew R Harper2,3, Florim Cuculi21Istituto Scienze della Vita, Scuola Superiore Sant'Anna, Pisa, Italy; 2Oxford University Hospitals, Oxford; 3Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United KingdomAbstract: Appropriate control of...

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Main Authors: Cuculi F, Harper AR, De Caterina AR
Format: Article
Language:English
Published: Dove Medical Press 2012-05-01
Series:Vascular Health and Risk Management
Online Access:http://www.dovepress.com/critical-evaluation-of-the-efficacy-and-tolerability-of-azilsartan-a9896
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author Cuculi F
Harper AR
De Caterina AR
author_facet Cuculi F
Harper AR
De Caterina AR
author_sort Cuculi F
collection DOAJ
description Alberto R De Caterina1,2, Andrew R Harper2,3, Florim Cuculi21Istituto Scienze della Vita, Scuola Superiore Sant'Anna, Pisa, Italy; 2Oxford University Hospitals, Oxford; 3Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United KingdomAbstract: Appropriate control of blood pressure (BP) in hypertensive patients still represents the major therapeutic goal in the treatment of hypertension. Despite the growing attention and wide range of antihypertensive agents available in the clinical scenario, the target of BP below the advised thresholds of 140/90 mmHg is, unfortunately, often unreached. For this reason, the search for new antihypertensive agents is still ongoing. Azilsartan medoxomil, a new angiotensin receptor blocker that has been recently introduced in the clinical arena, represents the eighth angiotensin receptor blocker currently available for BP control. The aim of this paper is to describe the efficacy and safety profile of this new compound, reviewing available data obtained from both pre-clinical and clinical studies.Keywords: azilsartan medoxomil, angiotensin receptor blocker, hypertension
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spelling doaj.art-8fcbe9e92ee54a5287e20d3d9818239a2022-12-22T03:56:20ZengDove Medical PressVascular Health and Risk Management1176-63441178-20482012-05-012012default299305Critical evaluation of the efficacy and tolerability of azilsartanCuculi FHarper ARDe Caterina ARAlberto R De Caterina1,2, Andrew R Harper2,3, Florim Cuculi21Istituto Scienze della Vita, Scuola Superiore Sant'Anna, Pisa, Italy; 2Oxford University Hospitals, Oxford; 3Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United KingdomAbstract: Appropriate control of blood pressure (BP) in hypertensive patients still represents the major therapeutic goal in the treatment of hypertension. Despite the growing attention and wide range of antihypertensive agents available in the clinical scenario, the target of BP below the advised thresholds of 140/90 mmHg is, unfortunately, often unreached. For this reason, the search for new antihypertensive agents is still ongoing. Azilsartan medoxomil, a new angiotensin receptor blocker that has been recently introduced in the clinical arena, represents the eighth angiotensin receptor blocker currently available for BP control. The aim of this paper is to describe the efficacy and safety profile of this new compound, reviewing available data obtained from both pre-clinical and clinical studies.Keywords: azilsartan medoxomil, angiotensin receptor blocker, hypertensionhttp://www.dovepress.com/critical-evaluation-of-the-efficacy-and-tolerability-of-azilsartan-a9896
spellingShingle Cuculi F
Harper AR
De Caterina AR
Critical evaluation of the efficacy and tolerability of azilsartan
Vascular Health and Risk Management
title Critical evaluation of the efficacy and tolerability of azilsartan
title_full Critical evaluation of the efficacy and tolerability of azilsartan
title_fullStr Critical evaluation of the efficacy and tolerability of azilsartan
title_full_unstemmed Critical evaluation of the efficacy and tolerability of azilsartan
title_short Critical evaluation of the efficacy and tolerability of azilsartan
title_sort critical evaluation of the efficacy and tolerability of azilsartan
url http://www.dovepress.com/critical-evaluation-of-the-efficacy-and-tolerability-of-azilsartan-a9896
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