Myoepithelial cells in pathology
Myoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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Series: | Journal of Pharmacy and Bioallied Sciences |
Subjects: | |
Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=Balachander |
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author | N Balachander K. M. K. Masthan N Aravindha babu V Anbazhagan |
author_facet | N Balachander K. M. K. Masthan N Aravindha babu V Anbazhagan |
author_sort | N Balachander |
collection | DOAJ |
description | Myoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between and over the acinar and ductal-lining cells, and they show features of both smooth muscle and epithelium. They play a vital role during expulsion of saliva and regulates the electrolytic exchange. They also perform as tumor suppressors and are considered to play a very important role in differentiation of various salivary gland tumors and help in the diagnosis of tumors. Neoplastic myoepithelial cells in both benign and malignant tumors can take numerous forms including epithelioid, plasmacytoid, spindle and clear cell variant, and this variability largely accounts for difficulties in histopathological diagnosis. |
first_indexed | 2024-12-22T00:46:55Z |
format | Article |
id | doaj.art-8fd09d58c34d4951a477f2474af69d3c |
institution | Directory Open Access Journal |
issn | 0975-7406 0976-4879 |
language | English |
last_indexed | 2024-12-22T00:46:55Z |
publishDate | 2015-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Pharmacy and Bioallied Sciences |
spelling | doaj.art-8fd09d58c34d4951a477f2474af69d3c2022-12-21T18:44:32ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792015-01-017519019310.4103/0975-7406.155898Myoepithelial cells in pathologyN BalachanderK. M. K. MasthanN Aravindha babuV AnbazhaganMyoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between and over the acinar and ductal-lining cells, and they show features of both smooth muscle and epithelium. They play a vital role during expulsion of saliva and regulates the electrolytic exchange. They also perform as tumor suppressors and are considered to play a very important role in differentiation of various salivary gland tumors and help in the diagnosis of tumors. Neoplastic myoepithelial cells in both benign and malignant tumors can take numerous forms including epithelioid, plasmacytoid, spindle and clear cell variant, and this variability largely accounts for difficulties in histopathological diagnosis.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=BalachanderMyoepithelial cellssalivary glandsepithelioid cells and basket cells |
spellingShingle | N Balachander K. M. K. Masthan N Aravindha babu V Anbazhagan Myoepithelial cells in pathology Journal of Pharmacy and Bioallied Sciences Myoepithelial cells salivary glands epithelioid cells and basket cells |
title | Myoepithelial cells in pathology |
title_full | Myoepithelial cells in pathology |
title_fullStr | Myoepithelial cells in pathology |
title_full_unstemmed | Myoepithelial cells in pathology |
title_short | Myoepithelial cells in pathology |
title_sort | myoepithelial cells in pathology |
topic | Myoepithelial cells salivary glands epithelioid cells and basket cells |
url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=Balachander |
work_keys_str_mv | AT nbalachander myoepithelialcellsinpathology AT kmkmasthan myoepithelialcellsinpathology AT naravindhababu myoepithelialcellsinpathology AT vanbazhagan myoepithelialcellsinpathology |