Myoepithelial cells in pathology

Myoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between...

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Main Authors: N Balachander, K. M. K. Masthan, N Aravindha babu, V Anbazhagan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=Balachander
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author N Balachander
K. M. K. Masthan
N Aravindha babu
V Anbazhagan
author_facet N Balachander
K. M. K. Masthan
N Aravindha babu
V Anbazhagan
author_sort N Balachander
collection DOAJ
description Myoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between and over the acinar and ductal-lining cells, and they show features of both smooth muscle and epithelium. They play a vital role during expulsion of saliva and regulates the electrolytic exchange. They also perform as tumor suppressors and are considered to play a very important role in differentiation of various salivary gland tumors and help in the diagnosis of tumors. Neoplastic myoepithelial cells in both benign and malignant tumors can take numerous forms including epithelioid, plasmacytoid, spindle and clear cell variant, and this variability largely accounts for difficulties in histopathological diagnosis.
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spelling doaj.art-8fd09d58c34d4951a477f2474af69d3c2022-12-21T18:44:32ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792015-01-017519019310.4103/0975-7406.155898Myoepithelial cells in pathologyN BalachanderK. M. K. MasthanN Aravindha babuV AnbazhaganMyoepithelial cells are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. Microscopically myoepithelial cells are thin and spindle-shaped and ultrastructurally they possess a number of Cytoplasmic processes that extend between and over the acinar and ductal-lining cells, and they show features of both smooth muscle and epithelium. They play a vital role during expulsion of saliva and regulates the electrolytic exchange. They also perform as tumor suppressors and are considered to play a very important role in differentiation of various salivary gland tumors and help in the diagnosis of tumors. Neoplastic myoepithelial cells in both benign and malignant tumors can take numerous forms including epithelioid, plasmacytoid, spindle and clear cell variant, and this variability largely accounts for difficulties in histopathological diagnosis.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=BalachanderMyoepithelial cellssalivary glandsepithelioid cells and basket cells
spellingShingle N Balachander
K. M. K. Masthan
N Aravindha babu
V Anbazhagan
Myoepithelial cells in pathology
Journal of Pharmacy and Bioallied Sciences
Myoepithelial cells
salivary glands
epithelioid cells and basket cells
title Myoepithelial cells in pathology
title_full Myoepithelial cells in pathology
title_fullStr Myoepithelial cells in pathology
title_full_unstemmed Myoepithelial cells in pathology
title_short Myoepithelial cells in pathology
title_sort myoepithelial cells in pathology
topic Myoepithelial cells
salivary glands
epithelioid cells and basket cells
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=5;spage=190;epage=193;aulast=Balachander
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AT kmkmasthan myoepithelialcellsinpathology
AT naravindhababu myoepithelialcellsinpathology
AT vanbazhagan myoepithelialcellsinpathology