International Consensus on a Dental Antibiotic Stewardship Core Outcome Set
ABSTRACT: Introduction: Antibiotic resistance is a global health crisis. Ensuring responsible, appropriate use (stewardship) is an important for keeping antibiotics working as long as possible. Around 10% of antibiotics across health care are prescribed by oral health care professionals, with high...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | International Dental Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S002065392300059X |
| _version_ | 1797825606522503168 |
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| author | Wendy Thompson Leanne Teoh Celine Pulcini Susie Sanderson David Williams Vanessa Carter Carole Pitkeathley Tanya Walsh |
| author_facet | Wendy Thompson Leanne Teoh Celine Pulcini Susie Sanderson David Williams Vanessa Carter Carole Pitkeathley Tanya Walsh |
| author_sort | Wendy Thompson |
| collection | DOAJ |
| description | ABSTRACT: Introduction: Antibiotic resistance is a global health crisis. Ensuring responsible, appropriate use (stewardship) is an important for keeping antibiotics working as long as possible. Around 10% of antibiotics across health care are prescribed by oral health care professionals, with high rates of unnecessary use. To maximise the value from research to optimise antibiotic use in dentistry, this study developed international consensus on a core outcome set for dental antibiotic stewardship. Methods: Candidate outcomes were sourced from a literature review. International participants were recruited via professional bodies, patient organisations, and social media, with at least 30 dentists, academics, and patient contributors in total. Outcomes scored “critical for inclusion” by >70% of the participants (dentists, academics, and patients) after 2 Delphi rounds were included in the core outcome set following a final consensus meeting. The study protocol was registered with the COMET Initiative and published in BMC Trials. Results: A total of 33 participants from 15 countries, including 8 low- and middle-income countries, completed both rounds of the Delphi study. Antibiotic use outcomes (eg, appropriateness of prescribing), adverse or poor outcomes (eg, complications from disease progression), and a patient-reported outcome were included in the final, agreed core set. Outcomes relating to quality, time, and cost were not included. Conclusions: This core outcome set for dental antibiotic stewardship represents the minimum which future studies of antibiotic stewardship in dentistry should report. By supporting researchers to design and report their studies in a way meaningful to multiple stakeholders and enabling international comparisons, the oral health profession's contribution to global efforts to tackle antibiotic resistance can be further improved. |
| first_indexed | 2024-03-13T10:56:26Z |
| format | Article |
| id | doaj.art-8fd0aeeb723542659fc3891a5cd307ff |
| institution | Directory Open Access Journal |
| issn | 0020-6539 |
| language | English |
| last_indexed | 2024-03-13T10:56:26Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Dental Journal |
| spelling | doaj.art-8fd0aeeb723542659fc3891a5cd307ff2023-05-17T04:22:24ZengElsevierInternational Dental Journal0020-65392023-06-01733456462International Consensus on a Dental Antibiotic Stewardship Core Outcome SetWendy Thompson0Leanne Teoh1Celine Pulcini2Susie Sanderson3David Williams4Vanessa Carter5Carole Pitkeathley6Tanya Walsh7University of Manchester, Manchester, United Kingdom; Corresponding author. Division of Dentistry, Coupland 3, Oxford Road, University of Manchester, M13 9PL, United Kingdom.University of Melbourne, Melbourne, AustraliaUniversité de Lorraine, Nancy, FranceFDI World Dental Federation, Geneva, SwitzerlandQueen Mary University of London, London, United KingdomJohannesburg, South AfricaBlyth, United KingdomUniversity of Manchester, Manchester, United KingdomABSTRACT: Introduction: Antibiotic resistance is a global health crisis. Ensuring responsible, appropriate use (stewardship) is an important for keeping antibiotics working as long as possible. Around 10% of antibiotics across health care are prescribed by oral health care professionals, with high rates of unnecessary use. To maximise the value from research to optimise antibiotic use in dentistry, this study developed international consensus on a core outcome set for dental antibiotic stewardship. Methods: Candidate outcomes were sourced from a literature review. International participants were recruited via professional bodies, patient organisations, and social media, with at least 30 dentists, academics, and patient contributors in total. Outcomes scored “critical for inclusion” by >70% of the participants (dentists, academics, and patients) after 2 Delphi rounds were included in the core outcome set following a final consensus meeting. The study protocol was registered with the COMET Initiative and published in BMC Trials. Results: A total of 33 participants from 15 countries, including 8 low- and middle-income countries, completed both rounds of the Delphi study. Antibiotic use outcomes (eg, appropriateness of prescribing), adverse or poor outcomes (eg, complications from disease progression), and a patient-reported outcome were included in the final, agreed core set. Outcomes relating to quality, time, and cost were not included. Conclusions: This core outcome set for dental antibiotic stewardship represents the minimum which future studies of antibiotic stewardship in dentistry should report. By supporting researchers to design and report their studies in a way meaningful to multiple stakeholders and enabling international comparisons, the oral health profession's contribution to global efforts to tackle antibiotic resistance can be further improved.http://www.sciencedirect.com/science/article/pii/S002065392300059XDentalAntibioticAntimicrobialPrescribingStewardshipOutcomes |
| spellingShingle | Wendy Thompson Leanne Teoh Celine Pulcini Susie Sanderson David Williams Vanessa Carter Carole Pitkeathley Tanya Walsh International Consensus on a Dental Antibiotic Stewardship Core Outcome Set International Dental Journal Dental Antibiotic Antimicrobial Prescribing Stewardship Outcomes |
| title | International Consensus on a Dental Antibiotic Stewardship Core Outcome Set |
| title_full | International Consensus on a Dental Antibiotic Stewardship Core Outcome Set |
| title_fullStr | International Consensus on a Dental Antibiotic Stewardship Core Outcome Set |
| title_full_unstemmed | International Consensus on a Dental Antibiotic Stewardship Core Outcome Set |
| title_short | International Consensus on a Dental Antibiotic Stewardship Core Outcome Set |
| title_sort | international consensus on a dental antibiotic stewardship core outcome set |
| topic | Dental Antibiotic Antimicrobial Prescribing Stewardship Outcomes |
| url | http://www.sciencedirect.com/science/article/pii/S002065392300059X |
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