Spatial patterns of noise-induced inner hair cell ribbon loss in the mouse mid-cochlea

Spatial patterns of noise-induced inner hair cell ribbon loss in the mouse mid-cochlea

Summary: In the mammalian cochlea, moderate acoustic overexposure leads to loss of ribbon-type synapse between the inner hair cell (IHC) and its postsynaptic spiral ganglion neuron (SGN), causing a reduced dynamic range of hearing but not a permanent threshold elevation. A prevailing view is that su...

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Bibliographic Details
Main Authors: Yan Lu, Jing Liu, Bei Li, Haoyu Wang, Fangfang Wang, Shengxiong Wang, Hao Wu, Hua Han, Yunfeng Hua
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Biological sciences
Neuroscience
Molecular neuroscience
Sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000464

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