Loss of Foxd4 Impacts Neurulation and Cranial Neural Crest Specification During Early Head Development

Loss of Foxd4 Impacts Neurulation and Cranial Neural Crest Specification During Early Head Development

The specification of anterior head tissue in the late gastrulation mouse embryo relies on signaling cues from the visceral endoderm and anterior mesendoderm (AME). Genetic loss-of-function studies have pinpointed a critical requirement of LIM homeobox 1 (LHX1) transcription factor in these tissues f...

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Bibliographic Details
Main Authors: Riley McMahon, Tennille Sibbritt, Nadar Aryamanesh, V. Pragathi Masamsetti, Patrick P. L. Tam
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Foxd4
head development
anterior neuroectoderm
neural tube defects
cranial neural crest
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.777652/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.777652/full

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