Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line

Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line

Chordomas are rare primary malignant tumours of notochordal origin usually arising along the axial skeleton with particular predilection of the skull base and sacrococcygeal region. Albeit usually slow-growing, chordomas can be aggressive mostly depending on their invasive behaviour and according to...

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Bibliographic Details
Main Authors: Francesca Pagani, Magdalena Gryzik, Elena Somenza, Manuela Cominelli, Piera Balzarini, Alberto Schreiber, Davide Mattavelli, Piero Nicolai, Francesco Doglietto, Pietro Luigi Poliani
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Personalized Medicine
Subjects:
chordoma
CH3 cell line
mTOR
rapamycin
Online Access:https://www.mdpi.com/2075-4426/13/3/425

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