A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine

Misuse of stimulants similar to amphetamine is a universal problem. These stimulants cause many complications in their abusers. However, myocardial infarction is rarely reported as a complication of amphetamine abuse. Herein, we report a man aged 42 years presented at the Emergency Department with t...

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Main Authors: Farhad Gholami, Seyed Hamzeh Hosseini, Amirhossein Ahmadi, Maryam Nabati
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2019-04-01
Series:Pharmaceutical and Biomedical Research
Subjects:
Online Access:http://pbr.mazums.ac.ir/article-1-226-en.html
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author Farhad Gholami
Seyed Hamzeh Hosseini
Amirhossein Ahmadi
Maryam Nabati
author_facet Farhad Gholami
Seyed Hamzeh Hosseini
Amirhossein Ahmadi
Maryam Nabati
author_sort Farhad Gholami
collection DOAJ
description Misuse of stimulants similar to amphetamine is a universal problem. These stimulants cause many complications in their abusers. However, myocardial infarction is rarely reported as a complication of amphetamine abuse. Herein, we report a man aged 42 years presented at the Emergency Department with the chief complaint of acute dyspnea following ice inhalation without history of dyspnea. Within the first hour and a half of admission, the patient was treated by nasal oxygen and bronchodilator aminophylline. However, he did not respond to the initial treatment and lost his consciousness; showed ventricular fibrillation, cardiac arrest, and hemodynamic instability. So, cardiopulmonary resuscitation was immediately initiated for him. The patient was intubated, mechanically ventilated. Also, the synchronized electrical shock was delivered 5 times (200-360 J) along with amiodarone (300 mg intravenously [IV] stat, then 1 mg/min IV infusion for 6 hours and next 0.5 mg/min for 18 hours) to treat the ventricular fibrillation. The arrhythmia was subsequently controlled, and his normal sinus rhythm was resumed. Two hours later, condition of the patient improved, and he was extubated. After two days, when the patient got stable, the echocardiography was performed, which was completely normal.
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spelling doaj.art-8fdbd112b143462eab6a3cb6a7be7b592022-12-22T00:51:10ZengMazandaran University of Medical SciencesPharmaceutical and Biomedical Research2423-44862423-44942019-04-01524952A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamineFarhad Gholami0Seyed Hamzeh Hosseini1Amirhossein Ahmadi2Maryam Nabati3 Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences Department of Cardiology, Faculty of Medicine, Mazandaran University of Medical Sciences Misuse of stimulants similar to amphetamine is a universal problem. These stimulants cause many complications in their abusers. However, myocardial infarction is rarely reported as a complication of amphetamine abuse. Herein, we report a man aged 42 years presented at the Emergency Department with the chief complaint of acute dyspnea following ice inhalation without history of dyspnea. Within the first hour and a half of admission, the patient was treated by nasal oxygen and bronchodilator aminophylline. However, he did not respond to the initial treatment and lost his consciousness; showed ventricular fibrillation, cardiac arrest, and hemodynamic instability. So, cardiopulmonary resuscitation was immediately initiated for him. The patient was intubated, mechanically ventilated. Also, the synchronized electrical shock was delivered 5 times (200-360 J) along with amiodarone (300 mg intravenously [IV] stat, then 1 mg/min IV infusion for 6 hours and next 0.5 mg/min for 18 hours) to treat the ventricular fibrillation. The arrhythmia was subsequently controlled, and his normal sinus rhythm was resumed. Two hours later, condition of the patient improved, and he was extubated. After two days, when the patient got stable, the echocardiography was performed, which was completely normal.http://pbr.mazums.ac.ir/article-1-226-en.htmlcrystal methamphetaminesevere dyspneacardiac arrestventricular fibrillationhemodynamic instability
spellingShingle Farhad Gholami
Seyed Hamzeh Hosseini
Amirhossein Ahmadi
Maryam Nabati
A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
Pharmaceutical and Biomedical Research
crystal methamphetamine
severe dyspnea
cardiac arrest
ventricular fibrillation
hemodynamic instability
title A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
title_full A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
title_fullStr A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
title_full_unstemmed A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
title_short A Case report of hemodynamic instability, cardiac arrest, and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
title_sort case report of hemodynamic instability cardiac arrest and acute severe dyspnea subsequent to inhalation of crystal methamphetamine
topic crystal methamphetamine
severe dyspnea
cardiac arrest
ventricular fibrillation
hemodynamic instability
url http://pbr.mazums.ac.ir/article-1-226-en.html
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