Allylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a

Allylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a

Vinothkumar Rajamanickam,* Tao Yan,* Liangrong Wu, Yanni Zhao, Xiaohong Xu, Heping Zhu, Xi Chen, Meihong Wang, Zhoudi Liu, Zhiguo Liu, Guang Liang, Yi Wang Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, People’s Re...

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Bibliographic Details
Main Authors: Rajamanickam V, Yan T, Wu L, Zhao Y, Xu X, Zhu H, Chen X, Wang M, Liu Z, Liang G, Wang Y
Format: Article
Language:English
Published: Dove Medical Press 2020-01-01
Series:Cancer Management and Research
Subjects:
gastric cancer
curcumin analog
reactive oxygen species
trxr1
foxo3a
Online Access:https://www.dovepress.com/allylated-curcumin-analog-ca6-inhibits-trxr1-and-leads-to-ros-dependen-peer-reviewed-article-CMAR

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