Effects of Vascular Comorbidity on Cognition in Multiple Sclerosis Are Partially Mediated by Changes in Brain Structure

Effects of Vascular Comorbidity on Cognition in Multiple Sclerosis Are Partially Mediated by Changes in Brain Structure

ObjectiveVascular comorbidities are associated with reduced cognitive performance and with changes in brain structure in people with multiple sclerosis (MS). Understanding causal pathways is necessary to support the design of interventions to mitigate the impacts of comorbidities, and to monitor the...

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Bibliographic Details
Main Authors: Ruth Ann Marrie, Ronak Patel, Chase R. Figley, Jennifer Kornelsen, James M. Bolton, Lesley A. Graff, Erin L. Mazerolle, Carl Helmick, Md Nasir Uddin, Teresa D. Figley, James J. Marriott, Charles N. Bernstein, John D. Fisk
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
MRI
cognition
diabetes
hypertension
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.910014/full

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