Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor
A biosensing membrane base on ferulic acid and glucose oxidase is synthesized onto a carbon paste electrode by electropolymerization via cyclic voltammetry in aqueous media at neutral pH at a single step. The developed biosensors exhibit a linear response from 0.082 to 34 mM glucose concentration, w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/12/3757 |
| _version_ | 1827689296373481472 |
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| author | Gabriela Valdés-Ramírez Laura Galicia |
| author_facet | Gabriela Valdés-Ramírez Laura Galicia |
| author_sort | Gabriela Valdés-Ramírez |
| collection | DOAJ |
| description | A biosensing membrane base on ferulic acid and glucose oxidase is synthesized onto a carbon paste electrode by electropolymerization via cyclic voltammetry in aqueous media at neutral pH at a single step. The developed biosensors exhibit a linear response from 0.082 to 34 mM glucose concentration, with a coefficient of determination R<sup>2</sup> equal to 0.997. The biosensors display a sensitivity of 1.1 μAmM<sup>−1</sup> cm<sup>−2</sup>, a detection limit of 0.025 mM, and 0.082 mM as glucose quantification limit. The studies reveal stable, repeatable, and reproducible biosensors response. The results indicate that the novel poly-ferulic acid membrane synthesized by electropolymerization is a promising method for glucose oxidase immobilization towards the development of glucose biosensors. The developed glucose biosensors exhibit a broader linear glucose response than other polymer-based glucose biosensors. |
| first_indexed | 2024-03-10T10:14:50Z |
| format | Article |
| id | doaj.art-8fe4c44508344491a4494d835bfe41c9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T10:14:50Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-8fe4c44508344491a4494d835bfe41c92023-11-22T00:56:27ZengMDPI AGMolecules1420-30492021-06-012612375710.3390/molecules26123757Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose BiosensorGabriela Valdés-Ramírez0Laura Galicia1Chemistry Department, Universidad Autónoma Metropolitana Unidad Iztapalapa, Av. San Rafael Atlixco 186, Leyes de Reforma 1ra Secc., 09340 Ciudad de Mexico, MexicoChemistry Department, Universidad Autónoma Metropolitana Unidad Iztapalapa, Av. San Rafael Atlixco 186, Leyes de Reforma 1ra Secc., 09340 Ciudad de Mexico, MexicoA biosensing membrane base on ferulic acid and glucose oxidase is synthesized onto a carbon paste electrode by electropolymerization via cyclic voltammetry in aqueous media at neutral pH at a single step. The developed biosensors exhibit a linear response from 0.082 to 34 mM glucose concentration, with a coefficient of determination R<sup>2</sup> equal to 0.997. The biosensors display a sensitivity of 1.1 μAmM<sup>−1</sup> cm<sup>−2</sup>, a detection limit of 0.025 mM, and 0.082 mM as glucose quantification limit. The studies reveal stable, repeatable, and reproducible biosensors response. The results indicate that the novel poly-ferulic acid membrane synthesized by electropolymerization is a promising method for glucose oxidase immobilization towards the development of glucose biosensors. The developed glucose biosensors exhibit a broader linear glucose response than other polymer-based glucose biosensors.https://www.mdpi.com/1420-3049/26/12/3757ferulic acidglucose oxidaseelectropolymerizationglucoseelectrochemical biosensor |
| spellingShingle | Gabriela Valdés-Ramírez Laura Galicia Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor Molecules ferulic acid glucose oxidase electropolymerization glucose electrochemical biosensor |
| title | Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor |
| title_full | Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor |
| title_fullStr | Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor |
| title_full_unstemmed | Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor |
| title_short | Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor |
| title_sort | biosensing membrane base on ferulic acid and glucose oxidase for an amperometric glucose biosensor |
| topic | ferulic acid glucose oxidase electropolymerization glucose electrochemical biosensor |
| url | https://www.mdpi.com/1420-3049/26/12/3757 |
| work_keys_str_mv | AT gabrielavaldesramirez biosensingmembranebaseonferulicacidandglucoseoxidaseforanamperometricglucosebiosensor AT lauragalicia biosensingmembranebaseonferulicacidandglucoseoxidaseforanamperometricglucosebiosensor |