Familial hypercholesterolemia: current status of the problem, treatment, and prevention

Familial hypercholesterolemia is the most common hereditary disease characterized by an increase in low density lipoprotein cholesterol levels and the premature development of atherosclerosis-related cardiovascular diseases. Diagnosis and treatment of such patients are associated with certain diffic...

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Main Authors: S. A. Bliznyuk, M. G. Bubnova, M. V. Ezhov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2020-11-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2532
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author S. A. Bliznyuk
M. G. Bubnova
M. V. Ezhov
author_facet S. A. Bliznyuk
M. G. Bubnova
M. V. Ezhov
author_sort S. A. Bliznyuk
collection DOAJ
description Familial hypercholesterolemia is the most common hereditary disease characterized by an increase in low density lipoprotein cholesterol levels and the premature development of atherosclerosis-related cardiovascular diseases. Diagnosis and treatment of such patients are associated with certain difficulties. This review presents data on the prevalence of familial hypercholesterolemia, identification of patients with such a diagnosis, prevention of adverse cardiovascular events, and also discusses the appointment of lipid-lowering therapy.
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spelling doaj.art-8fe9162a54d3454380fc3f8f078e45e32023-03-13T07:23:29Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252020-11-0119510.15829/1728-8800-2020-25322178Familial hypercholesterolemia: current status of the problem, treatment, and preventionS. A. Bliznyuk0M. G. Bubnova1M. V. Ezhov2ФГВУ Национальный медицинский исследовательский центр терапии и профилактической медицины Минздрава РоссииФГВУ Национальный медицинский исследовательский центр терапии и профилактической медицины Минздрава РоссииФГБУ Национальный медицинский исследовательский центр кардиологии Минздрава РоссииFamilial hypercholesterolemia is the most common hereditary disease characterized by an increase in low density lipoprotein cholesterol levels and the premature development of atherosclerosis-related cardiovascular diseases. Diagnosis and treatment of such patients are associated with certain difficulties. This review presents data on the prevalence of familial hypercholesterolemia, identification of patients with such a diagnosis, prevention of adverse cardiovascular events, and also discusses the appointment of lipid-lowering therapy.https://cardiovascular.elpub.ru/jour/article/view/2532гетерозиготная семейная гиперхолестеринемияхолестерин липопротеинов низкой плотностигиполипидемическая терапиястатины
spellingShingle S. A. Bliznyuk
M. G. Bubnova
M. V. Ezhov
Familial hypercholesterolemia: current status of the problem, treatment, and prevention
Кардиоваскулярная терапия и профилактика
гетерозиготная семейная гиперхолестеринемия
холестерин липопротеинов низкой плотности
гиполипидемическая терапия
статины
title Familial hypercholesterolemia: current status of the problem, treatment, and prevention
title_full Familial hypercholesterolemia: current status of the problem, treatment, and prevention
title_fullStr Familial hypercholesterolemia: current status of the problem, treatment, and prevention
title_full_unstemmed Familial hypercholesterolemia: current status of the problem, treatment, and prevention
title_short Familial hypercholesterolemia: current status of the problem, treatment, and prevention
title_sort familial hypercholesterolemia current status of the problem treatment and prevention
topic гетерозиготная семейная гиперхолестеринемия
холестерин липопротеинов низкой плотности
гиполипидемическая терапия
статины
url https://cardiovascular.elpub.ru/jour/article/view/2532
work_keys_str_mv AT sabliznyuk familialhypercholesterolemiacurrentstatusoftheproblemtreatmentandprevention
AT mgbubnova familialhypercholesterolemiacurrentstatusoftheproblemtreatmentandprevention
AT mvezhov familialhypercholesterolemiacurrentstatusoftheproblemtreatmentandprevention