CD44 Promotes Lung Cancer Cell Metastasis through ERK–ZEB1 Signaling

CD44 Promotes Lung Cancer Cell Metastasis through ERK–ZEB1 Signaling

Lung cancer is a malignancy with high mortality worldwide, and metastasis occurs at a high frequency even when cancer spread is not detectable at primary operation. Cancer stemness plays an important role in malignant cancer behavior, treatment resistance, and cancer metastasis. Therefore, understan...

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Bibliographic Details
Main Authors: Yen-Yun Wang, Anupama Vadhan, Ping-Ho Chen, Yen-Lung Lee, Chih-Yeh Chao, Kuang-Hung Cheng, Yu-Chiuan Chang, Stephen Chu-Sung Hu, Shyng-Shiou F. Yuan
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
CD44
lung cancer
ERK
ZEB1
metastasis
Online Access:https://www.mdpi.com/2072-6694/13/16/4057

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