Whole brain radiation therapy does not improve the overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastasis

Whole brain radiation therapy does not improve the overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastasis

Abstract Background Leptomeningeal metastasis (LM) is a devastating and terminal complication of advanced non-small-cell lung cancer (NSCLC), especially in patients harboring epidermal growth factor receptor (EGFR) mutations. The role of whole brain radiation therapy (WBRT) in the treatment of EGFR-...

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Bibliographic Details
Main Authors: Weiwei Yan, Yang Liu, Ji Li, Anqin Han, Li Kong, Jinming Yu, Hui Zhu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Radiation Oncology
Subjects:
Non-small cell lung cancer
Leptomeningeal metastasis
EGFR mutations
WBRT
Survival
Treatment response
Online Access:http://link.springer.com/article/10.1186/s13014-019-1376-z

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