Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial
Background and Aims: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB i...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
|
| Series: | Journal of Anaesthesiology Clinical Pharmacology |
| Subjects: | |
| Online Access: | http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=4;spage=610;epage=615;aulast=Ghaderi |
| _version_ | 1818083460353359872 |
|---|---|
| author | Kamal Ghaderi Khaled Rahmani Nasser Rahmanpanah Shoaleh Shami Farhad Zahedi Karim Nasseri |
| author_facet | Kamal Ghaderi Khaled Rahmani Nasser Rahmanpanah Shoaleh Shami Farhad Zahedi Karim Nasseri |
| author_sort | Kamal Ghaderi |
| collection | DOAJ |
| description | Background and Aims: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB in distal forearm and hand surgery.
Material and Methods: In this randomized double-blind trial, which was conducted after obtaining institutional ethical committee approval, 60 patients were enrolled and randomly divided into two groups. In both groups, the analgesic base of the block was 20 mL lidocaine 0.5% that was supplemented by 1 μg/kg dexmedetomidine in the LD group or 1 mL of 0.9% saline in the LS group. Patients were evaluated for the onset and duration of sensory block, time of the first request for postoperative analgesic, and analgesic request frequency during the first 24 h after surgery.
Results: Sensory block onset in the LD group (7.1 ± 1.4 min) compared to the LS group (8.4 ± 1.4) was faster (P = 0.008). Duration of the sensory block in LD group (49.7 ± 7.2 min) was longer than LS group (33.3 ± 2.6) (P < 0.001). Compared to LS group, time of the first request for postoperative analgesic in LD group was later (P = 0.6), and had lesser analgesic requests during the first 24 h after surgery (P < 0.001).
Conclusion: Based on our study's finding, adding dexmedetomidine to lidocaine in the MFBB increases the duration of sensory block. |
| first_indexed | 2024-12-10T19:38:21Z |
| format | Article |
| id | doaj.art-8ff03f5aeee34efb86c2aea7743ce3a2 |
| institution | Directory Open Access Journal |
| issn | 0970-9185 |
| language | English |
| last_indexed | 2024-12-10T19:38:21Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Anaesthesiology Clinical Pharmacology |
| spelling | doaj.art-8ff03f5aeee34efb86c2aea7743ce3a22022-12-22T01:36:03ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852021-01-0137461061510.4103/joacp.JOACP_54_20Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trialKamal GhaderiKhaled RahmaniNasser RahmanpanahShoaleh ShamiFarhad ZahediKarim NasseriBackground and Aims: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB in distal forearm and hand surgery. Material and Methods: In this randomized double-blind trial, which was conducted after obtaining institutional ethical committee approval, 60 patients were enrolled and randomly divided into two groups. In both groups, the analgesic base of the block was 20 mL lidocaine 0.5% that was supplemented by 1 μg/kg dexmedetomidine in the LD group or 1 mL of 0.9% saline in the LS group. Patients were evaluated for the onset and duration of sensory block, time of the first request for postoperative analgesic, and analgesic request frequency during the first 24 h after surgery. Results: Sensory block onset in the LD group (7.1 ± 1.4 min) compared to the LS group (8.4 ± 1.4) was faster (P = 0.008). Duration of the sensory block in LD group (49.7 ± 7.2 min) was longer than LS group (33.3 ± 2.6) (P < 0.001). Compared to LS group, time of the first request for postoperative analgesic in LD group was later (P = 0.6), and had lesser analgesic requests during the first 24 h after surgery (P < 0.001). Conclusion: Based on our study's finding, adding dexmedetomidine to lidocaine in the MFBB increases the duration of sensory block.http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=4;spage=610;epage=615;aulast=Ghaderianalgesicsanesthesiadexmedetomidinenerve blockpain |
| spellingShingle | Kamal Ghaderi Khaled Rahmani Nasser Rahmanpanah Shoaleh Shami Farhad Zahedi Karim Nasseri Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial Journal of Anaesthesiology Clinical Pharmacology analgesics anesthesia dexmedetomidine nerve block pain |
| title | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
| title_full | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
| title_fullStr | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
| title_full_unstemmed | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
| title_short | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
| title_sort | comparison of lidocaine dexmedetomidine and lidocaine saline on the characteristics of the modified forearm bier block a clinical trial |
| topic | analgesics anesthesia dexmedetomidine nerve block pain |
| url | http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=4;spage=610;epage=615;aulast=Ghaderi |
| work_keys_str_mv | AT kamalghaderi comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial AT khaledrahmani comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial AT nasserrahmanpanah comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial AT shoalehshami comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial AT farhadzahedi comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial AT karimnasseri comparisonoflidocainedexmedetomidineandlidocainesalineonthecharacteristicsofthemodifiedforearmbierblockaclinicaltrial |