Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2

Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2

Lysyl oxidase-like 2 (LOXL2) has emerged as a promising therapeutic target against metastatic/invasive tumors and organ and tissue fibrosis. LOXL2 catalyzes the oxidative deamination of lysine and hydroxylysine residues in extracellular matrix (ECM) proteins to promote crosslinking of these proteins...

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Bibliographic Details
Main Authors: Alex A. Meier, Hee-Jung Moon, Ronald Toth, Ewa Folta-Stogniew, Krzysztof Kuczera, C. Russell Middaugh, Minae Mure
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
lysyl oxidase-like 2
scavenger receptor cysteine-rich
extracellular matrix
hydrodynamic radius
analytical ultracentrifugation
isoelectric points
Online Access:https://www.mdpi.com/2218-273X/11/12/1846

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