Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos
Summary: We investigated the awareness, perceived usefulness, and use of genetic testing among Hispanic and Latino individuals. Annual follow-up surveys for the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) from 2019 to April 2020 assessed participants’ level of awareness and use of ge...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | HGG Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266624772200077X |
| _version_ | 1811315716310171648 |
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| author | Kurt D. Christensen Mengran Zhang Lauren N. Galbraith Einat Granot-Hershkovitz Sarah C. Nelson Sara Gonzalez Maria Argos Krista M. Perreira Martha L. Daviglus Carmen R. Isasi Jianwen Cai Gregory A. Talavera Carrie L. Blout Zawatsky Robert C. Green Rosario Isasi Robert Kaplan Tamar Sofer |
| author_facet | Kurt D. Christensen Mengran Zhang Lauren N. Galbraith Einat Granot-Hershkovitz Sarah C. Nelson Sara Gonzalez Maria Argos Krista M. Perreira Martha L. Daviglus Carmen R. Isasi Jianwen Cai Gregory A. Talavera Carrie L. Blout Zawatsky Robert C. Green Rosario Isasi Robert Kaplan Tamar Sofer |
| author_sort | Kurt D. Christensen |
| collection | DOAJ |
| description | Summary: We investigated the awareness, perceived usefulness, and use of genetic testing among Hispanic and Latino individuals. Annual follow-up surveys for the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) from 2019 to April 2020 assessed participants’ level of awareness and use of genetic tests to determine disease risks, likelihood of passing disease to children, disease treatment, or drug selection. They also were asked to rate the usefulness of the tests for managing a person’s health on a 1 (not at all useful) to 10 (extremely useful) scale. There were 5,769 HCHS/SOL participants who completed at least one survey question. Of the target population, 55.2% was aware of at least one type of genetic test. Awareness varied between HCHS/SOL enrollment sites and was higher among individuals who had higher educational attainment and had higher incomes. Only 3.3% of the target population reported receiving one or more of the tests described. HCHS/SOL individuals rated the usefulness as 8.4, on average, with lower scores observed among U.S.-born individuals compared to individuals born outside the United States, with differences by HCHS/SOL enrollment sites. In conclusion, while awareness of genetic testing among Hispanic and Latino individuals varies by location, education, and income, perceptions about its usefulness are high while experiences with testing are rare. Results identify groups and locations that may benefit from greater outreach about the capabilities of genetic testing and precision medicine. |
| first_indexed | 2024-04-13T11:35:18Z |
| format | Article |
| id | doaj.art-8ff2e6c54d70411d90040259888b69d3 |
| institution | Directory Open Access Journal |
| issn | 2666-2477 |
| language | English |
| last_indexed | 2024-04-13T11:35:18Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | HGG Advances |
| spelling | doaj.art-8ff2e6c54d70411d90040259888b69d32022-12-22T02:48:27ZengElsevierHGG Advances2666-24772023-01-0141100160Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of LatinosKurt D. Christensen0Mengran Zhang1Lauren N. Galbraith2Einat Granot-Hershkovitz3Sarah C. Nelson4Sara Gonzalez5Maria Argos6Krista M. Perreira7Martha L. Daviglus8Carmen R. Isasi9Jianwen Cai10Gregory A. Talavera11Carrie L. Blout Zawatsky12Robert C. Green13Rosario Isasi14Robert Kaplan15Tamar Sofer16PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA; Broad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Population Medicine, Harvard Medical School, Boston, MA, USADivision of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA 02115, USAPRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA; Departments of Epidemiology and Biostatistics, Boston University of Public Health, Boston, MA, USADivision of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA, USADepartment of Biostatistics, University of Washington, Seattle, WA, USADepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USASchool of Public Health, University of Illinois at Chicago, Chicago, IL, USADepartment of Social Medicine, University of North Carolina, School of Medicine, Chapel Hill, NC, USAInstitute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA; Feinberg School of Medicine, Northwestern University, Chicago, IL, USADepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USACollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USASouth Bay Latino Research Center, Department of Psychology, San Diego State University, San Diego, CA, USABroad Institute of Harvard and MIT, Cambridge, MA, USA; Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA; MGH Institute of Health Professions, Boston, MA, USA; Ariadne Labs, Boston, MA, USABroad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA; Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA; Ariadne Labs, Boston, MA, USADepartment of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USADepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USADepartment of Medicine, Harvard Medical School, Boston, MA, USA; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women’s Hospital, 221 Longwood Avenue, Suite 225C, Boston, MA 02115, USA; Corresponding authorSummary: We investigated the awareness, perceived usefulness, and use of genetic testing among Hispanic and Latino individuals. Annual follow-up surveys for the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) from 2019 to April 2020 assessed participants’ level of awareness and use of genetic tests to determine disease risks, likelihood of passing disease to children, disease treatment, or drug selection. They also were asked to rate the usefulness of the tests for managing a person’s health on a 1 (not at all useful) to 10 (extremely useful) scale. There were 5,769 HCHS/SOL participants who completed at least one survey question. Of the target population, 55.2% was aware of at least one type of genetic test. Awareness varied between HCHS/SOL enrollment sites and was higher among individuals who had higher educational attainment and had higher incomes. Only 3.3% of the target population reported receiving one or more of the tests described. HCHS/SOL individuals rated the usefulness as 8.4, on average, with lower scores observed among U.S.-born individuals compared to individuals born outside the United States, with differences by HCHS/SOL enrollment sites. In conclusion, while awareness of genetic testing among Hispanic and Latino individuals varies by location, education, and income, perceptions about its usefulness are high while experiences with testing are rare. Results identify groups and locations that may benefit from greater outreach about the capabilities of genetic testing and precision medicine.http://www.sciencedirect.com/science/article/pii/S266624772200077Xgenetic testing, ELSIHispanic or Latinoawarenesssurveyperceived usefulnesspopulation-based study |
| spellingShingle | Kurt D. Christensen Mengran Zhang Lauren N. Galbraith Einat Granot-Hershkovitz Sarah C. Nelson Sara Gonzalez Maria Argos Krista M. Perreira Martha L. Daviglus Carmen R. Isasi Jianwen Cai Gregory A. Talavera Carrie L. Blout Zawatsky Robert C. Green Rosario Isasi Robert Kaplan Tamar Sofer Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos HGG Advances genetic testing, ELSI Hispanic or Latino awareness survey perceived usefulness population-based study |
| title | Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos |
| title_full | Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos |
| title_fullStr | Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos |
| title_full_unstemmed | Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos |
| title_short | Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos |
| title_sort | awareness and utilization of genetic testing among hispanic and latino adults living in the us the hispanic community health study study of latinos |
| topic | genetic testing, ELSI Hispanic or Latino awareness survey perceived usefulness population-based study |
| url | http://www.sciencedirect.com/science/article/pii/S266624772200077X |
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