Growth Differentiation Factor-15 and Syndecan-1 Are Potential Biomarkers of Cardiac and Renal Involvement in Classical Fabry Disease under Enzyme Replacement Therapy

Growth Differentiation Factor-15 and Syndecan-1 Are Potential Biomarkers of Cardiac and Renal Involvement in Classical Fabry Disease under Enzyme Replacement Therapy

Background and Aims: Inflammation and endothelial damage play a pivotal role in Fabry disease (FD) manifestations. In daily clinical practice, FD is mainly monitored by traditional biomarkers of target organ injury, such as serum creatinine and proteinuria, which provide no information about inflamm...

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Bibliographic Details
Main Authors: Paulo C. Gregório, Gilson Biagini, Regiane S. da Cunha, Júlia Budag, Ana Maria Martins, Lara Valiño Rivas, Elberth M. Schiefer, Maria Dolores Sánchez-Niño, Alberto Ortiz, Andréa E. M. Stinghen, Fellype C. Barreto
Format: Article
Language:English
Published: Karger Publishers 2022-01-01
Series:Kidney & Blood Pressure Research
Subjects:
fabry disease
enzyme replacement therapy
biomarkers
inflammation
oxidative stress
Online Access:https://www.karger.com/Article/FullText/521329

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