Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

<p>Abstract</p> <p>Background</p> <p>The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1) is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4<sup>+</sup> T lymphocytes. Tax permanently...

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Bibliographic Details
Main Authors: Bonnet Amandine, Randrianarison-Huetz Voahangy, Nzounza Patrycja, Nedelec Martine, Chazal Maxime, Waast Laetitia, Pene Sabrina, Bazarbachi Ali, Mahieux Renaud, Bénit Laurence, Pique Claudine
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Retrovirology
Subjects:
Retrovirus
Leukemia
NF-kappaB
Ubiquitin
SUMO
Nuclear speckles
Online Access:http://www.retrovirology.com/content/9/1/77

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