Rola angiogenezy w rozwoju nowotworów
Angiogenesis, the formation of new blood vessels from existing vasculature, is a complex multi-step processinitiated by the secretion and action of soluble angiogenic factors. Thus degradation of extracellular matrixproteins and activation, proliferation, migration and organization into tubular stru...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2010-02-01
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| Series: | Menopause Review |
| Subjects: | |
| Online Access: | http://www.termedia.pl/Rola-angiogenezy-w-rozwoju-nowotworow,4,14203,1,0.html |
| _version_ | 1811234919751352320 |
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| author | Paweł Sadłecki Małgorzata Walentowicz-Sadłecka Marek Grabiec |
| author_facet | Paweł Sadłecki Małgorzata Walentowicz-Sadłecka Marek Grabiec |
| author_sort | Paweł Sadłecki |
| collection | DOAJ |
| description | Angiogenesis, the formation of new blood vessels from existing vasculature, is a complex multi-step processinitiated by the secretion and action of soluble angiogenic factors. Thus degradation of extracellular matrixproteins and activation, proliferation, migration and organization into tubular structures of vascular endothelialcells and pericytes takes place. Formation of new blood vessels plays a key role in physiological processes involvingneovascularization, such as ovulation, placentation and embryogenesis. Moreover, angiogenesis is crucialfor benign and malignant neoplastic processes. Invasive cancer growth occurs as a result of formation of bloodvessels within a tumour that enable its growth, infiltration of tissues and genesis of metastases. |
| first_indexed | 2024-04-12T11:44:06Z |
| format | Article |
| id | doaj.art-8ff7988abee64209a8f5baa93b5efd36 |
| institution | Directory Open Access Journal |
| issn | 1643-8876 |
| language | English |
| last_indexed | 2024-04-12T11:44:06Z |
| publishDate | 2010-02-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Menopause Review |
| spelling | doaj.art-8ff7988abee64209a8f5baa93b5efd362022-12-22T03:34:27ZengTermedia Publishing HouseMenopause Review1643-88762010-02-011412831Rola angiogenezy w rozwoju nowotworówPaweł SadłeckiMałgorzata Walentowicz-SadłeckaMarek GrabiecAngiogenesis, the formation of new blood vessels from existing vasculature, is a complex multi-step processinitiated by the secretion and action of soluble angiogenic factors. Thus degradation of extracellular matrixproteins and activation, proliferation, migration and organization into tubular structures of vascular endothelialcells and pericytes takes place. Formation of new blood vessels plays a key role in physiological processes involvingneovascularization, such as ovulation, placentation and embryogenesis. Moreover, angiogenesis is crucialfor benign and malignant neoplastic processes. Invasive cancer growth occurs as a result of formation of bloodvessels within a tumour that enable its growth, infiltration of tissues and genesis of metastases.http://www.termedia.pl/Rola-angiogenezy-w-rozwoju-nowotworow,4,14203,1,0.htmlangiogenesisneoplasmspro-angiogenic factors |
| spellingShingle | Paweł Sadłecki Małgorzata Walentowicz-Sadłecka Marek Grabiec Rola angiogenezy w rozwoju nowotworów Menopause Review angiogenesis neoplasms pro-angiogenic factors |
| title | Rola angiogenezy w rozwoju nowotworów |
| title_full | Rola angiogenezy w rozwoju nowotworów |
| title_fullStr | Rola angiogenezy w rozwoju nowotworów |
| title_full_unstemmed | Rola angiogenezy w rozwoju nowotworów |
| title_short | Rola angiogenezy w rozwoju nowotworów |
| title_sort | rola angiogenezy w rozwoju nowotworow |
| topic | angiogenesis neoplasms pro-angiogenic factors |
| url | http://www.termedia.pl/Rola-angiogenezy-w-rozwoju-nowotworow,4,14203,1,0.html |
| work_keys_str_mv | AT pawełsadłecki rolaangiogenezywrozwojunowotworow AT małgorzatawalentowiczsadłecka rolaangiogenezywrozwojunowotworow AT marekgrabiec rolaangiogenezywrozwojunowotworow |