Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell

Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell

Microglia belong to tissue-resident macrophages of the central nervous system (CNS), representing the primary innate immune cells. This cell type constitutes ~7% of non-neuronal cells in the mammalian brain and has a variety of biological roles integral to homeostasis and pathophysiology from the la...

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Bibliographic Details
Main Authors: Iasonas Dermitzakis, Maria Eleni Manthou, Soultana Meditskou, Marie-Ève Tremblay, Steven Petratos, Lida Zoupi, Marina Boziki, Evangelia Kesidou, Constantina Simeonidou, Paschalis Theotokis
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Current Issues in Molecular Biology
Subjects:
microglia
origin
yolk sac
progeny
molecular cues
development
Online Access:https://www.mdpi.com/1467-3045/45/3/171

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