Platelets in ITP: Victims in Charge of Their Own Fate?

Platelets in ITP: Victims in Charge of Their Own Fate?

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved, but at least involve autoantibody-dependent and/or cytotoxic T cell mediated platelet clearance and impaired megakaryopoiesis. In addition...

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Bibliographic Details
Main Authors: Vivianne S. Nelson, Anne-Tess C. Jolink, Sufia N. Amini, Jaap Jan Zwaginga, Tanja Netelenbos, John W. Semple, Leendert Porcelijn, Masja de Haas, Martin R. Schipperus, Rick Kapur
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
ITP
platelet immune functions
platelet microparticles
Online Access:https://www.mdpi.com/2073-4409/10/11/3235

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